HitPredict

Interactor 1: LAIR1 (Q6GTX8)
Leukocyte-associated immunoglobulin-like receptor 1 (LAIR-1) (hLAIR1) (CD antigen CD305)
Gene: LAIR1

Interactor 2: LAIR1 (Q6GTX8)
Leukocyte-associated immunoglobulin-like receptor 1 (LAIR-1) (hLAIR1) (CD antigen CD305)
Gene: LAIR1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	1.00	0.724

Property	Details
Experiments	21982860
Identification Methods	pull down, protein array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Ig_2~Ig_2
Common GO terms	GO:0002250 - adaptive immune response GO:0002764 - immune response-regulating signaling pathway GO:0005886 - plasma membrane GO:0035579 - specific granule membrane GO:0070821 - tertiary granule membrane
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 287 Hs			1 287
+	Hs
		1233114 LAIR1_HUMAN (1-287): 2.98e-102: 302: 100.00		LAIR2_HUMAN (1-145): 1.1e-55: 178: 79.31
+	Hs
		850768 KI2L2_HUMAN (17-284): 2.33e-72: 227: 22.88		KI2L1_HUMAN (17-284): 1.12e-71: 226: 22.14
+	Hs
		850797 KI2L2_HUMAN (17-284): 2.33e-72: 227: 22.88		KI2S2_HUMAN (1-162): 1.61e-38: 139: 21.21
+	Hs
		850796 KI2L2_HUMAN (17-284): 2.33e-72: 227: 22.88		KI3L1_HUMAN (1-154): 3.66e-35: 133: 21.66
+	Hs
		850769 KI2L1_HUMAN (17-284): 1.12e-71: 226: 22.14		KI3L1_HUMAN (1-154): 3.66e-35: 133: 21.66
+	Hs
		850802 KI2L2_HUMAN (17-284): 2.33e-72: 227: 22.88		KI2S3_HUMAN (1-151): 7.67e-36: 131: 23.23
+	Hs
		850775 KI2L1_HUMAN (17-284): 1.12e-71: 226: 22.14		KI2S3_HUMAN (1-151): 7.67e-36: 131: 23.23
+	Hs
		850801 KI2L2_HUMAN (17-284): 2.33e-72: 227: 22.88		KI3S1_HUMAN (1-162): 3.67e-29: 116: 23.46
+	Hs
		1325617 LIRB4_HUMAN (1-246): 3.62e-56: 188: 25.59		LIRB2_HUMAN (28-150): 1.16e-22: 99.5: 24.00
+	Hs
		1340129 LIRB4_HUMAN (1-246): 3.62e-56: 188: 25.59		LIRB1_HUMAN (28-168): 2.79e-22: 98.4: 22.38
+	Hs
		850890 KI2S2_HUMAN (1-162): 1.61e-38: 139: 21.21		KI2S2_HUMAN (1-162): 1.61e-38: 139: 21.21
+	Hs
		850892 KI2S2_HUMAN (1-162): 1.61e-38: 139: 21.21		KI2S5_HUMAN (1-162): 7.08e-37: 134: 20.61
+	Hs
		47608 A0A8I5QEB2_HUMAN (1-151): 3.5e-37: 138: 23.38		KI2S5_HUMAN (1-162): 7.08e-37: 134: 20.61
+	Hs
		850863 KI2S2_HUMAN (1-162): 1.61e-38: 139: 21.21		KI3L1_HUMAN (1-154): 3.66e-35: 133: 21.66
+	Hs
		850891 KI2S2_HUMAN (1-162): 1.61e-38: 139: 21.21		KI2S3_HUMAN (1-151): 7.67e-36: 131: 23.23
+	Hs
		850893 KI2S2_HUMAN (1-162): 1.61e-38: 139: 21.21		KI2S1_HUMAN (1-162): 3.68e-35: 130: 21.21
+	Hs
		850898 KI2S2_HUMAN (1-162): 1.61e-38: 139: 21.21		KI2LA_HUMAN (1-164): 1.4e-34: 130: 23.35