Protein: KI2S5
Killer cell immunoglobulin-like receptor 2DS5 (CD158 antigen-like family member G) (Natural killer-associated transcript 9) (NKAT-9) (CD antigen CD158g)

Gene: KI2S5, KIR2DS5
Organism: Homo sapiens
Interactions: 15
UniProt ID: Q14953

Gene Ontology (top 5):
GO:0002764 - immune response-regulating signaling pathway
GO:0005886 - plasma membrane
GO:0006955 - immune response
GO:0016020 - membrane
GO:0030110 - HLA-C specific inhibitory MHC class I receptor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

850892

KI2S2
Killer cell immunoglobulin-like receptor 2DS2

2

14

High-throughput

0.712

High

47052

A0A583ZBW8
HLA-C protein

1

20

Small-scale

0.647

High

520844

HLAC
HLA class I histocompatibility antigen, C alpha chain

1

20

Small-scale

0.647

High

47608

A0A8I5QEB2
Killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 3

1

14

High-throughput

0.575

High

1133836

KI2S3
Killer cell immunoglobulin-like receptor 2DS3

1

14

High-throughput

0.575

High

230962

TYOBP
TYRO protein tyrosine kinase-binding protein

1

3

Small-scale

0.534

High

1133852

EDEM2
ER degradation-enhancing alpha-mannosidase-like protein 2

1

3

High-throughput

0.445

High

1133854

ALG9
Alpha-1,2-mannosyltransferase ALG9

1

2

High-throughput

0.445

High

66198

MET15
12S rRNA N(4)-cytidine methyltransferase METTL15

1

1

High-throughput

0.407

High

1133849

TBB8
Tubulin beta-8 chain

1

2

High-throughput

0.407

High

1133853

PARL
Presenilin-associated rhomboid-like protein, mitochondrial

1

4

High-throughput

0.407

High

1133855

SH3B4
SH3 domain-binding protein 4

1

1

High-throughput

0.407

High

665099

COT2
COUP transcription factor 2

1

0

High-throughput

0.232

Low

1133850

FUBP1
Far upstream element-binding protein 1

1

0

High-throughput

0.232

Low

1133851

F118B
Protein FAM118B

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025