Protein: LIRB4
Leukocyte immunoglobulin-like receptor subfamily B member 4 (B4) (CD85 antigen-like family member K) (Immunoglobulin-like transcript 3) (ILT-3) (Leukocyte immunoglobulin-like receptor 5) (LIR-5) (Monocyte inhibitory receptor HM18) (CD antigen CD85k)

Gene: LIRB4, LILRB4
Organism: Homo sapiens
Interactions: 36
UniProt ID: Q8NHJ6

Gene Ontology (top 5):
GO:0001968 - fibronectin binding
GO:0002250 - adaptive immune response
GO:0002507 - tolerance induction
GO:0002669 - positive regulation of T cell anergy
GO:0002725 - negative regulation of T cell cytokine production

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

658912

PTPRD
Receptor-type tyrosine-protein phosphatase delta

2

5

High-throughput

0.811

High

1325617

LIRB2
Leukocyte immunoglobulin-like receptor subfamily B member 2

2

17

High-throughput

0.712

High

661305

AT2B4
Plasma membrane calcium-transporting ATPase 4

3

7

High-throughput

0.662

High

1064720

CD47
Leukocyte surface antigen CD47

3

0

High-throughput

0.634

High

1032626

AT2B2
Plasma membrane calcium-transporting ATPase 2

2

5

High-throughput

0.628

High

1162299

AT2B3
Plasma membrane calcium-transporting ATPase 3

2

6

High-throughput

0.628

High

1221112

CD276
CD276 antigen

1

7

High-throughput

0.618

High

878060

AGRE5
Adhesion G protein-coupled receptor E5

2

7

High-throughput

0.601

High

711158

PTN6
Tyrosine-protein phosphatase non-receptor type 6

2

20

Small-scale

0.576

High

409455

HLAA
HLA class I histocompatibility antigen, A alpha chain

1

20

High-throughput

0.575

High

1102730

PTPRS
Receptor-type tyrosine-protein phosphatase S

1

6

High-throughput

0.575

High

1340129

LIRB1
Leukocyte immunoglobulin-like receptor subfamily B member 1

1

17

High-throughput

0.575

High

1307885

ARMC8
Armadillo repeat-containing protein 8

2

3

High-throughput

0.574

High

1340135

GID8
Glucose-induced degradation protein 8 homolog

2

4

High-throughput

0.574

High

1340136

MKLN1
Muskelin

2

3

High-throughput

0.574

High

618199

AMD
Peptidyl-glycine alpha-amidating monooxygenase

1

1

High-throughput

0.536

High

627378

AT2B1
Plasma membrane calcium-transporting ATPase 1

1

7

High-throughput

0.536

High

834682

TNFL9
Tumor necrosis factor ligand superfamily member 9

1

3

High-throughput

0.536

High

1062176

PCDH1
Protocadherin-1

1

6

High-throughput

0.536

High

1272708

MAEA
E3 ubiquitin-protein transferase MAEA

1

4

High-throughput

0.536

High

533721

CLUS
Clusterin

1

0

High-throughput

0.513

High

1340130

TIP
T-cell immunomodulatory protein

1

0

High-throughput

0.513

High

1250497

RBP10
Ran-binding protein 10

1

5

High-throughput

0.489

High

1340131

RN145
RING finger protein 145

1

3

High-throughput

0.489

High

1340132

RMD5A
E3 ubiquitin-protein transferase RMND5A

1

2

High-throughput

0.489

High

271727

HIP1R
Huntingtin-interacting protein 1-related protein

1

2

High-throughput

0.445

High

575168

IDE
Insulin-degrading enzyme

1

0

High-throughput

0.426

High

1335557

DGLB
Diacylglycerol lipase-beta

1

0

High-throughput

0.426

High

1340137

PCDGD
Protocadherin gamma-B1

1

0

High-throughput

0.426

High

934016

PLTP
Phospholipid transfer protein

1

1

High-throughput

0.407

High

1228389

SE1L3
Protein sel-1 homolog 3

1

1

High-throughput

0.407

High

1340134

TBG2
Tubulin gamma-2 chain

1

7

High-throughput

0.407

High

1309294

GID4
Glucose-induced degradation protein 4 homolog

2

0

High-throughput

0.328

High

1340133

PAAT
ATPase PAAT

2

0

High-throughput

0.328

High

629966

BTF3
Transcription factor BTF3

1

0

High-throughput

0.249

Low

827448

MLH1
DNA mismatch repair protein Mlh1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025