HitPredict

Interactor 1: MYO1C (O00159)
Unconventional myosin-Ic (Myosin I beta) (MMI-beta) (MMIb)
Gene: MYO1C

Interactor 2: DREB (Q16643)
Drebrin (Developmentally-regulated brain protein)
Gene: DBN1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0007015 - actin filament organization GO:0015629 - actin cytoskeleton
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1063 Hs			1 649
+	Hs
		318330 MYO1D_HUMAN (45-1056): 0: 1076: 39.87		DREB_HUMAN (1-649): 3.27e-95: 308: 100.00
+	Hs
		227889 MYO1B_HUMAN (46-1058): 0: 1058: 39.77		DREB_HUMAN (1-649): 3.27e-95: 308: 100.00
+	Hs
		1160810 MYO5A_HUMAN (8-1058): 0: 1038: 27.30		DREB_HUMAN (1-649): 3.27e-95: 308: 100.00
+	Hs
		772825 MYH9_HUMAN (5-974): 0: 994: 29.37		DREB_HUMAN (1-649): 3.27e-95: 308: 100.00
+	Hs
		1160796 MYO5B_HUMAN (46-959): 0: 971: 30.60		DREB_HUMAN (1-649): 3.27e-95: 308: 100.00
+	Hs
		551605 MYH9_HUMAN (5-974): 0: 994: 29.37		NFH_HUMAN (129-649): 3.41e-20: 97.6: 11.43
+	Hs
		772875 MYH9_HUMAN (5-974): 0: 994: 29.37		MICA3_HUMAN (205-646): 4.7e-10: 65.2: 9.90
+	Hs
		772931 MYH9_HUMAN (5-974): 0: 994: 29.37		TITIN_HUMAN (184-598): 2.53e-09: 62.9: 10.29
+	Sc
		587334 MYO5_YEAST (41-752): 0: 570: 41.82		ABP1_YEAST (4-512): 1.46e-30: 128: 13.41
+	Ce
		145080 HUM6_CAEEL (47-794): 1.88e-152: 502: 37.85		UNC89_CAEEL (187-643): 6.91e-20: 97.1: 9.60
+	Hs
		1091674 MYO1E_HUMAN (859-986): 1.78e-10: 67.4: 31.76		DREB_HUMAN (1-649): 3.27e-95: 308: 100.00
+	Hs
		215920 MYO1E_HUMAN (859-986): 1.78e-10: 67.4: 31.76		SYNJ1_HUMAN (126-645): 3.15e-29: 126: 9.77