HitPredict

Interactor 1: LS14A (Q8ND56)
Protein LSM14 homolog A (Protein FAM61A) (Protein SCD6 homolog) (Putative alpha-synuclein-binding protein) (AlphaSNBP) (RNA-associated protein 55A) (hRAP55) (hRAP55A)
Gene: LSM14A

Interactor 2: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	29509190
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 463 Hs			1 530
+	Hs
		370028 LS14A_HUMAN (1-463): 2.65e-117: 353: 100.00		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		1269521 LS14B_HUMAN (2-401): 1.81e-74: 240: 45.70		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		370354 LS14B_HUMAN (2-401): 1.81e-74: 240: 45.70		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		225402 MED14_HUMAN (54-294): 6.38e-25: 110: 15.39		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		1270066 PCLO_HUMAN (51-386): 1.86e-17: 87.7: 11.47		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		1269810 CHD7_HUMAN (82-373): 1.03e-10: 66.5: 12.00		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		302306 SC31A_HUMAN (69-294): 1.26e-10: 66.1: 13.16		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		225328 MED14_HUMAN (54-294): 6.38e-25: 110: 15.39		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Mm
		101423 F8VPR5_MOUSE (74-395): 2.42e-21: 99.6: 12.42		ESR1_MOUSE (9-529): 4.88e-134: 403: 43.72
+	Hs
		370607 CHD7_HUMAN (82-373): 1.03e-10: 66.5: 12.00		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Mm
		101427 F8VPR5_MOUSE (74-395): 2.42e-21: 99.6: 12.42		RXRG_MOUSE (13-499): 5.3e-117: 355: 22.56
+	Mm
		57035 MED14_MOUSE (54-294): 8.12e-27: 116: 14.23		ERR2_MOUSE (69-499): 5.26e-107: 328: 31.11
+	Hs
		225354 MED14_HUMAN (54-294): 6.38e-25: 110: 15.39		HNF4A_HUMAN (94-502): 1.21e-107: 331: 23.30
+	Hs
		225330 MED14_HUMAN (54-294): 6.38e-25: 110: 15.39		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Mm
		101828 F8WI37_MOUSE (32-373): 9.59e-14: 76.1: 10.42		ERR2_MOUSE (69-499): 5.26e-107: 328: 31.11
+	Mm
		1142676 KMT2C_MOUSE (32-373): 9.59e-14: 76.1: 10.42		ERR2_MOUSE (69-499): 5.26e-107: 328: 31.11
+	Hs
		782677 CHD7_HUMAN (82-373): 1.03e-10: 66.5: 12.00		HNF4A_HUMAN (94-502): 1.21e-107: 331: 23.30
+	Hs
		377760 CHD7_HUMAN (82-373): 1.03e-10: 66.5: 12.00		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Hs
		225338 MED14_HUMAN (54-294): 6.38e-25: 110: 15.39		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59
+	Hs
		487803 CHD7_HUMAN (82-373): 1.03e-10: 66.5: 12.00		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59