HitPredict

Interactor 1: PHC3 (Q8NDX5)
Polyhomeotic-like protein 3 (Early development regulatory protein 3) (Homolog of polyhomeotic 3) (hPH3)
Gene: PHC3

Interactor 2: FBLN5 (Q9UBX5)
Fibulin-5 (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50)
Gene: FBLN5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 983 Hs			1 448
+	Hs
		1220900 PHC2_HUMAN (30-566): 3.66e-17: 88.9: 27.02		FBLN5_HUMAN (1-448): 1.31e-70: 232: 100.00
+	Hs
		869552 ATN1_HUMAN (165-912): 2.72e-09: 63.5: 10.43		FBLN5_HUMAN (1-448): 1.31e-70: 232: 100.00
+	Hs
		254237 SHAN3_HUMAN (131-980): 3.49e-30: 131: 11.53		MEGF6_HUMAN (20-339): 5.25e-25: 110: 34.23
+	Hs
		1231801 SHAN3_HUMAN (131-980): 3.49e-30: 131: 11.53		LTBP4_HUMAN (9-286): 1.82e-19: 93.6: 24.32
+	Hs
		804330 SHAN3_HUMAN (131-980): 3.49e-30: 131: 11.53		NOTC1_HUMAN (5-391): 1.25e-18: 91.1: 13.16
+	Hs
		1016988 SHAN3_HUMAN (131-980): 3.49e-30: 131: 11.53		FBLN3_HUMAN (3-214): 1.13e-14: 78: 22.62
+	Hs
		980523 SHAN3_HUMAN (131-980): 3.49e-30: 131: 11.53		NOTC2_HUMAN (3-312): 4.71e-11: 67.2: 15.67
+	Hs
		1316288 SHAN3_HUMAN (131-980): 3.49e-30: 131: 11.53		LTBP3_HUMAN (10-320): 9.7e-11: 66.4: 18.12
+	Hs
		328048 SHAN3_HUMAN (131-980): 3.49e-30: 131: 11.53		FBLN4_HUMAN (3-191): 6.34e-10: 62.9: 27.18
+	Dm
		246871 Q8IQA6_DROME (51-896): 8.34e-11: 68.5: 9.09		TENM_DROME (206-440): 5.16e-26: 113: 11.69
+	Hs
		254233 ATN1_HUMAN (165-912): 2.72e-09: 63.5: 10.43		MEGF6_HUMAN (20-339): 5.25e-25: 110: 34.23
+	Hs
		869493 ATN1_HUMAN (165-912): 2.72e-09: 63.5: 10.43		LTBP4_HUMAN (9-286): 1.82e-19: 93.6: 24.32
+	Dm
		422802 Q8IQA6_DROME (51-896): 8.34e-11: 68.5: 9.09		NOTCH_DROME (3-343): 1.45e-14: 78.4: 12.89
+	Hs
		869462 ATN1_HUMAN (165-912): 2.72e-09: 63.5: 10.43		FBLN3_HUMAN (3-214): 1.13e-14: 78: 22.62
+	Dm
		114000 M9PB30_DROME (1-399): 2.92e-11: 70.4: 10.03		CUBN_DROME (287-405): 6.31e-12: 70.3: 15.79
+	Hs
		869465 ATN1_HUMAN (165-912): 2.72e-09: 63.5: 10.43		LTBP1_HUMAN (4-286): 1.43e-13: 75.2: 19.14
+	Hs
		869450 ATN1_HUMAN (165-912): 2.72e-09: 63.5: 10.43		FBLN2_HUMAN (28-369): 2.11e-12: 71.4: 21.91
+	Hs
		327971 ATN1_HUMAN (165-912): 2.72e-09: 63.5: 10.43		FBLN4_HUMAN (3-191): 6.34e-10: 62.9: 27.18
+	Hs
		612833 ATN1_HUMAN (165-912): 2.72e-09: 63.5: 10.43		FBLN1_HUMAN (245-332): 8.14e-09: 59.8: 32.96