HitPredict

Interactor 1: TOLIP (Q9H0E2)
Toll-interacting protein
Gene: TOLLIP

Interactor 2: TRAF6 (Q9Y4K3)
TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (Interleukin-1 signal transducer) (RING finger protein 85) (RING-type E3 ubiquitin transferase TRAF6)
Gene: TRAF6

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.60 0.60 0.601

The method score is based on:

Property Details
Experiments 31077413, 19716405
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0031624 - ubiquitin conjugating enzyme binding
GO:0032991 - protein-containing complex
GO:0045087 - innate immune response
and 2 others

more...
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 274
Hs

1 522
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024