HitPredict

Interactor 1: KMT2C (Q8NEZ4)
Histone-lysine N-methyltransferase 2C (Lysine N-methyltransferase 2C) (EC 2.1.1.364) (Homologous to ALR protein) (Myeloid/lymphoid or mixed-lineage leukemia protein 3)
Gene: KMT2C

Interactor 2: DYL2 (Q96FJ2)
Dynein light chain 2, cytoplasmic (8 kDa dynein light chain b) (DLC8b) (Dynein light chain LC8-type 2)
Gene: DYNLL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	33961781, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 4911 Hs			1 89
+	Hs
		928397 KMT2C_HUMAN (1-4911): 0: 2416: 100.00		DYL1_HUMAN (1-89): 1.8e-47: 147: 93.26
+	Hs
		928314 EZH2_HUMAN (4563-4893): 4.31e-83: 294: 20.99		DYL1_HUMAN (1-89): 1.8e-47: 147: 93.26
+	Hs
		928302 CHD4_HUMAN (83-436): 3.08e-38: 161: 13.56		DYL1_HUMAN (1-89): 1.8e-47: 147: 93.26
+	Hs
		1059788 CHD4_HUMAN (83-436): 3.08e-38: 161: 13.56		DYL2_HUMAN (1-89): 7.09e-47: 146: 100.00