HitPredict

Interactor 1: Q6PF32 (Q6PF32)
Mothers against decapentaplegic homolog (MAD homolog) (Mothers against DPP homolog) (SMAD family member)
Gene: smad1.L

Interactor 2: Q7ZTB4 (Q7ZTB4)
Inner nuclear membrane protein Man1 (LEM domain-containing protein 3)
Gene: lemd3.S

Species: Xenopus laevis

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.50	0.457

Property	Details
Experiments	12642484
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 464 Xl			1 781
+	Xl
		1244233 Q6PF37_XENLA (3-464): 0: 625: 80.13		Q7ZTB4_XENLA (1-781): 0: 1096: 100.00
+	Xl
		1235202 Q6IRR4_XENLA (3-464): 0: 549: 54.85		Q7ZTB4_XENLA (1-781): 0: 1096: 100.00
+	Hs
		1154031 SMAD1_HUMAN (1-464): 0: 662: 95.48		MAN1_HUMAN (5-778): 0: 982: 49.95
+	Hs
		1406703 SMAD5_HUMAN (2-464): 0: 637: 90.30		MAN1_HUMAN (5-778): 0: 982: 49.95
+	Hs
		181958 SMAD9_HUMAN (3-464): 0: 631: 79.70		MAN1_HUMAN (5-778): 0: 982: 49.95
+	Hs
		1014669 SMAD3_HUMAN (3-464): 0: 567: 58.00		MAN1_HUMAN (5-778): 0: 982: 49.95
+	Hs
		1153951 SMAD2_HUMAN (3-464): 0: 550: 54.85		MAN1_HUMAN (5-778): 0: 982: 49.95
+	Xl
		1281779 Q9YGP9_XENLA (6-458): 1.02e-143: 425: 34.88		Q7ZTB4_XENLA (1-781): 0: 1096: 100.00
+	Dm
		837140 MAD_DROME (2-464): 0: 614: 73.22		MAN1_DROME (184-761): 0: 609: 20.73
+	Dm
		355860 O96660_DROME (6-464): 0: 521: 51.21		MAN1_DROME (184-761): 0: 609: 20.73
+	Dm
		1216763 Q5U110_DROME (142-439): 4.11e-67: 226: 24.92		MAN1_DROME (184-761): 0: 609: 20.73
+	Hs
		685701 SMAD5_HUMAN (2-464): 0: 637: 90.30		U2AF2_HUMAN (605-744): 1.55e-31: 131: 20.13
+	Hs
		685504 SMAD3_HUMAN (3-464): 0: 567: 58.00		U2AF2_HUMAN (605-744): 1.55e-31: 131: 20.13
+	Hs
		685591 SMAD2_HUMAN (3-464): 0: 550: 54.85		U2AF2_HUMAN (605-744): 1.55e-31: 131: 20.13