Interactor 1: SPSB3 (Q6PJ21)
SPRY domain-containing SOCS box protein 3 (SSB-3)
Gene: SPSB3
Interactor 2: CUL5 (Q93034)
Cullin-5 (CUL-5) (Vasopressin-activated calcium-mobilizing receptor 1) (VACM-1)
Gene: CUL5
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.85 | 0.60 | 0.716 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 28514442, 31253590, 33961781, 21145461, unassigned3799 |
| Identification Methods | affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005634 - nucleus GO:0005829 - cytosol GO:0019005 - SCF ubiquitin ligase complex GO:0031466 - Cul5-RING ubiquitin ligase complex GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
