HitPredict

Interactor 1: MPRIP (Q6WCQ1)
Myosin phosphatase Rho-interacting protein (M-RIP) (Rho-interacting protein 3) (RIP3) (p116Rip)
Gene: MPRIP

Interactor 2: PACN3 (Q9UKS6)
Protein kinase C and casein kinase substrate in neurons protein 3 (SH3 domain-containing protein 6511)
Gene: PACSIN3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1025 Hs			1 424
+	Hs
		1250770 MPRIP_HUMAN (1-1025): 9.69e-126: 410: 100.00		PACN1_HUMAN (4-422): 1.2e-86: 272: 48.86
+	Hs
		1250804 MPRIP_HUMAN (1-1025): 9.69e-126: 410: 100.00		PACN2_HUMAN (4-422): 1.77e-78: 252: 48.96
+	Hs
		1459685 SWP70_HUMAN (370-824): 7.3e-58: 212: 19.22		PACN2_HUMAN (4-422): 1.77e-78: 252: 48.96
+	Hs
		1235026 PKHA7_HUMAN (336-980): 2.5e-41: 167: 13.51		PACN2_HUMAN (4-422): 1.77e-78: 252: 48.96
+	Hs
		773069 MYH9_HUMAN (528-991): 3.25e-16: 86.3: 11.35		PACN3_HUMAN (1-424): 2.79e-93: 289: 100.00
+	Hs
		1431721 TARA_HUMAN (645-1023): 9.99e-10: 65.1: 12.98		PACN3_HUMAN (1-424): 2.79e-93: 289: 100.00
+	Hs
		1417651 TARA_HUMAN (645-1023): 9.99e-10: 65.1: 12.98		PACN1_HUMAN (4-422): 1.2e-86: 272: 48.86
+	Hs
		1070502 PKHA7_HUMAN (336-980): 2.5e-41: 167: 13.51		FCHO2_HUMAN (12-369): 1.89e-43: 164: 14.96
+	Hs
		1431723 TARA_HUMAN (645-1023): 9.99e-10: 65.1: 12.98		PACN2_HUMAN (4-422): 1.77e-78: 252: 48.96
+	Hs
		772764 MYH9_HUMAN (528-991): 3.25e-16: 86.3: 11.35		FCHO2_HUMAN (12-369): 1.89e-43: 164: 14.96
+	Hs
		772771 MYH9_HUMAN (528-991): 3.25e-16: 86.3: 11.35		MYO1E_HUMAN (35-422): 2.55e-39: 152: 14.42
+	Hs
		1154118 MYH14_HUMAN (595-972): 3.71e-09: 63.1: 14.89		ITSN1_HUMAN (346-421): 2.69e-15: 80.6: 28.95