HitPredict

Interactor 1: LEG9 (O00182)
Galectin-9 (Gal-9) (Ecalectin) (Tumor antigen HOM-HD-21)
Gene: LGALS9

Interactor 2: AT2B4 (P23634)
Plasma membrane calcium-transporting ATPase 4 (PMCA4) (EC 7.2.2.10) (Matrix-remodeling-associated protein 1) (Plasma membrane calcium ATPase isoform 4) (Plasma membrane calcium pump isoform 4)
Gene: ATP2B4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.79	0.60	0.691

Property	Details
Experiments	26186194, 28514442, 33961781, unassigned3799
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0010629 - negative regulation of gene expression
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 355 Hs			1 1241
+	Hs
		661283 LEG9C_HUMAN (1-355): 6.65e-143: 410: 94.10		AT2B4_HUMAN (1-1241): 0: 1304: 100.00
+	Hs
		661276 LEG9B_HUMAN (1-355): 3.7e-142: 408: 94.94		AT2B4_HUMAN (1-1241): 0: 1304: 100.00
+	Hs
		127280 LEG8_HUMAN (1-355): 1.79e-106: 316: 30.85		AT2B4_HUMAN (1-1241): 0: 1304: 100.00
+	Hs
		1162287 LEG9B_HUMAN (1-355): 3.7e-142: 408: 94.94		AT2B3_HUMAN (1-1241): 0: 1164: 71.63
+	Hs
		125222 LEG9_HUMAN (1-355): 3.81e-147: 421: 100.00		AT2B1_HUMAN (1-1241): 0: 1149: 72.46
+	Hs
		627353 LEG9C_HUMAN (1-355): 6.65e-143: 410: 94.10		AT2B1_HUMAN (1-1241): 0: 1149: 72.46
+	Hs
		127342 LEG8_HUMAN (1-355): 1.79e-106: 316: 30.85		AT2B3_HUMAN (1-1241): 0: 1164: 71.63
+	Hs
		127315 LEG8_HUMAN (1-355): 1.79e-106: 316: 30.85		AT2B2_HUMAN (4-1241): 0: 1158: 68.64
+	Hs
		609581 LEG3_HUMAN (5-147): 7.97e-42: 148: 38.00		AT2B4_HUMAN (1-1241): 0: 1304: 100.00
+	Hs
		125139 LEG9_HUMAN (1-355): 3.81e-147: 421: 100.00		AT1A1_HUMAN (30-1060): 0: 759: 23.78
+	Hs
		420346 LEG3_HUMAN (5-147): 7.97e-42: 148: 38.00		AT1A1_HUMAN (30-1060): 0: 759: 23.78