HitPredict

Interactor 1: ASXL2 (Q76L83)
Putative Polycomb group protein ASXL2 (Additional sex combs-like protein 2)
Gene: ASXL2

Interactor 2: SKI8 (Q9GZS3)
Superkiller complex protein 8 (Ski8) (Meiotic recombination REC14 protein homolog) (WD repeat-containing protein 61) [Cleaved into: Superkiller complex protein 8, N-terminally processed (WD repeat-containing protein 61, N-terminally processed)]
Gene: SKIC8

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36180891
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 1435 Hs			1 305
+	Hs
		965047 ASXL2_HUMAN (1-1435): 0: 646: 100.00		WDR5_HUMAN (179-304): 2.51e-41: 147: 33.33
+	Hs
		1421195 ASXL3_HUMAN (71-1435): 1.68e-11: 71.6: 11.39		SKI8_HUMAN (1-305): 9.09e-102: 301: 100.00
+	Hs
		1058904 ZO1_HUMAN (94-832): 3.48e-28: 126: 11.56		FBXW7_HUMAN (91-303): 7.84e-64: 215: 24.30
+	Hs
		1129693 MDC1_HUMAN (18-1385): 1.9e-26: 120: 9.53		SNR40_HUMAN (2-216): 1.1e-59: 195: 22.42
+	Hs
		1380165 PRR36_HUMAN (82-1102): 9.4e-17: 88.5: 11.17		FBXW7_HUMAN (91-303): 7.84e-64: 215: 24.30
+	Hs
		161502 KMT2D_HUMAN (412-1023): 4.44e-14: 80: 13.50		FBXW7_HUMAN (91-303): 7.84e-64: 215: 24.30
+	Hs
		1273854 MICA3_HUMAN (375-1077): 3.93e-12: 73.7: 11.61		FBXW7_HUMAN (91-303): 7.84e-64: 215: 24.30
+	Hs
		965128 CBP_HUMAN (384-1028): 8.22e-23: 108: 13.64		WDR5_HUMAN (179-304): 2.51e-41: 147: 33.33
+	Hs
		161443 KMT2D_HUMAN (412-1023): 4.44e-14: 80: 13.50		WDR5_HUMAN (179-304): 2.51e-41: 147: 33.33
+	Hs
		965078 ASXL1_HUMAN (337-1435): 1.53e-13: 78.1: 12.18		WDR5_HUMAN (179-304): 2.51e-41: 147: 33.33
+	Hs
		965221 ASXL3_HUMAN (71-1435): 1.68e-11: 71.6: 11.39		WDR5_HUMAN (179-304): 2.51e-41: 147: 33.33
+	Hs
		161486 KMT2D_HUMAN (412-1023): 4.44e-14: 80: 13.50		WDR5B_HUMAN (179-304): 8.24e-38: 138: 30.95
+	Mm
		965395 KMT2C_MOUSE (414-967): 1.55e-09: 65.4: 14.65		WDR5_MOUSE (179-304): 2.51e-41: 147: 33.33
+	Hs
		161490 KMT2D_HUMAN (412-1023): 4.44e-14: 80: 13.50		POC1A_HUMAN (2-133): 1.59e-33: 128: 20.46
+	Dm
		1481151 Q9VLS7_DROME (453-948): 4.42e-11: 70: 14.93		FBXW7_DROME (217-304): 2.95e-19: 90.2: 24.72
+	Dm
		1481107 Q9VLS7_DROME (453-948): 4.42e-11: 70: 14.93		POC1_DROME (219-305): 5.39e-19: 88.1: 24.14