HitPredict

Interactor 1: Q7JX87 (Q7JX87)
1-Cys peroxiredoxin
Gene: Prx6c

Interactor 2: Q9W022 (Q9W022)
GEO01508p1 (RE49388p)
Gene: DmelCG8993

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	1.00	0.737

Property	Details
Experiments	22036573, 38944040
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	1-cysPrx_C~Thioredoxin, AhpC-TSA~Thioredoxin
Common GO terms	GO:0045454 - cell redox homeostasis
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 220 Dm			1 142
+	Dm
		1262835 Q7JX87_DROME (1-220): 5.1e-98: 285: 100.00		THIO2_DROME (34-138): 1.25e-35: 120: 31.13
+	Dm
		54045 A1Z892_DROME (1-220): 5.27e-98: 285: 99.09		THIO2_DROME (34-138): 1.25e-35: 120: 31.13
+	Dm
		54118 A1Z892_DROME (1-220): 5.27e-98: 285: 99.09		Q9W022_DROME (1-142): 7.95e-35: 119: 100.00
+	Dm
		1262836 Q7JX87_DROME (1-220): 5.1e-98: 285: 100.00		PDIA6_DROME (9-126): 4.88e-29: 111: 21.01
+	Dm
		54046 A1Z892_DROME (1-220): 5.27e-98: 285: 99.09		PDIA6_DROME (9-126): 4.88e-29: 111: 21.01
+	Mm
		148100 PRDX6_MOUSE (1-217): 1.15e-91: 270: 53.21		THIOM_MOUSE (37-139): 5.09e-36: 123: 46.60
+	Mm
		1021693 PRDX2_MOUSE (2-202): 1.55e-83: 248: 30.73		THIOM_MOUSE (37-139): 5.09e-36: 123: 46.60
+	Ss
		910371 P73348_SYNY3 (1-217): 3.02e-81: 243: 48.39		THIO_SYNY3 (33-138): 3.79e-38: 126: 27.36
+	Hs
		528200 PRDX2_HUMAN (2-202): 3.4e-83: 247: 30.73		THIO_HUMAN (34-138): 2.24e-35: 119: 25.47
+	Ss
		910425 P73348_SYNY3 (1-217): 3.02e-81: 243: 48.39		THIO1_SYNY3 (40-124): 1.07e-36: 123: 34.12
+	Mm
		776005 PRDX1_MOUSE (2-200): 3.47e-81: 242: 31.86		THIOM_MOUSE (37-139): 5.09e-36: 123: 46.60
+	At
		1319812 BAS1B_ARATH (2-199): 4.38e-80: 242: 33.17		TRXX_ARATH (17-138): 2.4e-35: 122: 29.84
+	Mm
		628294 PRDX3_MOUSE (2-196): 4.38e-80: 241: 29.00		THIOM_MOUSE (37-139): 5.09e-36: 123: 46.60
+	Mm
		148340 PRDX4_MOUSE (2-202): 1.95e-79: 240: 28.29		THIOM_MOUSE (37-139): 5.09e-36: 123: 46.60
+	Hs
		528237 PRDX1_HUMAN (2-200): 4.79e-82: 244: 31.37		THIO_HUMAN (34-138): 2.24e-35: 119: 25.47
+	Os
		1232160 BAS1_ORYSJ (2-199): 7.96e-80: 241: 32.18		TRXX_ORYSJ (8-141): 3.45e-35: 121: 26.47
+	At
		1319811 BAS1A_ARATH (2-199): 4.21e-79: 239: 33.17		TRXX_ARATH (17-138): 2.4e-35: 122: 29.84
+	Hs
		566569 PRDX3_HUMAN (2-203): 1.79e-81: 245: 26.70		PDIA4_HUMAN (35-140): 1.07e-28: 111: 28.44
+	Hs
		732359 PRDX2_HUMAN (2-202): 3.4e-83: 247: 30.73		TXND5_HUMAN (39-138): 1.27e-28: 109: 24.04
+	Rn
		801674 PRDX4_RAT (2-202): 6.75e-79: 239: 28.29		PDIA4_RAT (2-137): 1.18e-26: 105: 18.44