Interactor 1: PSMF1 (Q92530)
Proteasome inhibitor PI31 subunit (hPI31)
Gene: PSMF1

Interactor 2: FBX7 (Q9Y3I1)
F-box only protein 7
Gene: FBXO7

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.981

The method score is based on:

Property Details
Experiments 25416956, 18495667, 26496610, 25910212, 27497298, 28514442, 27503909, 33961781, 35182481, 31515488
Identification Methods two hybrid, affinity chromatography technology, pull down, two hybrid prey pooling approach, two hybrid array, validated two hybrid, anti tag coimmunoprecipitation, two hybrid bait and prey pooling approach
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains PI31_Prot_N~PI31_Prot_N
Common GO terms GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0046982 - protein heterodimerization activity
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 271
Hs

1 522
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024