HitPredict

Interactor 1: HDAC2 (Q92769)
Histone deacetylase 2 (HD2) (EC 3.5.1.98) (Protein deacylase HDAC2) (EC 3.5.1.-)
Gene: HDAC2

Interactor 2: RBP56 (Q92804)
TATA-binding protein-associated factor 2N (68 kDa TATA-binding protein-associated factor) (TAF(II)68) (TAFII68) (RNA-binding protein 56)
Gene: TAF15

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	30737378, 26949739
Identification Methods	affinity chromatography technology, cross-linking study
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 488 Hs			1 592
+	Hs
		967312 HDAC2_HUMAN (1-488): 0: 707: 100.00		EWS_HUMAN (4-383): 3.73e-35: 142: 32.96
+	Hs
		726963 HDAC2_HUMAN (1-488): 0: 707: 100.00		FUS_HUMAN (8-381): 2.72e-32: 132: 39.28
+	Hs
		436042 HDAC2_HUMAN (1-488): 0: 707: 100.00		CO1A2_HUMAN (9-226): 7.7e-09: 61: 10.05
+	Hs
		177264 HDAC3_HUMAN (10-431): 0: 574: 58.26		EWS_HUMAN (4-383): 3.73e-35: 142: 32.96
+	Mm
		1142753 HDA10_MOUSE (12-394): 1.09e-139: 418: 23.06		EWS_MOUSE (4-383): 9.82e-32: 132: 33.26
+	Hs
		967488 HDAC6_HUMAN (11-363): 6.94e-102: 332: 24.04		EWS_HUMAN (4-383): 3.73e-35: 142: 32.96
+	Hs
		727075 HDAC6_HUMAN (11-363): 6.94e-102: 332: 24.04		FUS_HUMAN (8-381): 2.72e-32: 132: 39.28
+	Hs
		212186 HDAC6_HUMAN (11-363): 6.94e-102: 332: 24.04		HTSF1_HUMAN (113-325): 5.58e-31: 130: 18.06
+	Hs
		1049668 HDAC6_HUMAN (11-363): 6.94e-102: 332: 24.04		EIF3A_HUMAN (314-591): 5.41e-22: 103: 18.21