HitPredict

Interactor 1: CBP (Q92793)
CREB-binding protein (Histone lysine acetyltransferase CREBBP) (EC 2.3.1.48) (Protein lactyltransferas CREBBP) (EC 2.3.1.-) (Protein-lysine acetyltransferase CREBBP) (EC 2.3.1.-)
Gene: CREBBP

Interactor 2: HIPK3 (Q9H422)
Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Androgen receptor-interacting nuclear protein kinase) (ANPK) (Fas-interacting serine/threonine-protein kinase) (FIST) (Homolog of protein kinase YAK1)
Gene: HIPK3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	28680062
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016604 - nuclear body
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2442 Hs			1 1215
+	Hs
		1270792 CBP_HUMAN (1-2442): 0: 1104: 100.00		HIPK2_HUMAN (1-1215): 0: 620: 47.53
+	Hs
		1206218 CBP_HUMAN (1-2442): 0: 1104: 100.00		HIPK1_HUMAN (1-1106): 8.16e-147: 476: 40.05
+	Hs
		625532 CBP_HUMAN (1-2442): 0: 1104: 100.00		CDK2_HUMAN (195-527): 5.35e-126: 391: 25.66
+	Hs
		999086 EP300_HUMAN (1-2426): 0: 874: 55.06		HIPK2_HUMAN (1-1215): 0: 620: 47.53
+	Hs
		681959 CBP_HUMAN (1-2442): 0: 1104: 100.00		AKT1_HUMAN (28-514): 3.85e-120: 382: 16.47
+	Hs
		850689 CBP_HUMAN (1-2442): 0: 1104: 100.00		KS6A3_HUMAN (137-496): 3.73e-97: 328: 17.68
+	Hs
		1071667 CBP_HUMAN (1-2442): 0: 1104: 100.00		KS6A2_HUMAN (194-496): 1.48e-96: 327: 19.32
+	Hs
		1073459 CBP_HUMAN (1-2442): 0: 1104: 100.00		KS6A1_HUMAN (153-529): 2.07e-94: 321: 18.63
+	Mm
		101422 F8VPR5_MOUSE (1-2442): 0: 1077: 95.67		KS6A3_MOUSE (137-496): 2.81e-97: 329: 17.68
+	Hs
		1044010 CBP_HUMAN (1-2442): 0: 1104: 100.00		DYR1A_HUMAN (195-524): 9.1e-56: 210: 39.47
+	Hs
		1270845 CBP_HUMAN (1-2442): 0: 1104: 100.00		DYR1B_HUMAN (197-524): 1.27e-54: 204: 37.46
+	Hs
		999084 EP300_HUMAN (1-2426): 0: 874: 55.06		SLK_HUMAN (177-984): 2.6e-130: 432: 17.18
+	At
		1105682 HAC1_ARATH (677-1887): 0: 897: 24.22		KSG7_ARATH (145-555): 2.95e-121: 381: 22.70
+	Hs
		999077 EP300_HUMAN (1-2426): 0: 874: 55.06		SIK2_HUMAN (188-1092): 1.83e-120: 397: 15.15
+	Hs
		625393 EP300_HUMAN (1-2426): 0: 874: 55.06		CDK2_HUMAN (195-527): 5.35e-126: 391: 25.66
+	Hs
		681812 EP300_HUMAN (1-2426): 0: 874: 55.06		AKT1_HUMAN (28-514): 3.85e-120: 382: 16.47
+	Hs
		998769 EP300_HUMAN (1-2426): 0: 874: 55.06		MK14_HUMAN (182-548): 2.07e-110: 351: 26.98
+	Hs
		998682 EP300_HUMAN (1-2426): 0: 874: 55.06		DYR1A_HUMAN (195-524): 9.1e-56: 210: 39.47
+	Hs
		999248 EP300_HUMAN (1-2426): 0: 874: 55.06		DYR1B_HUMAN (197-524): 1.27e-54: 204: 37.46
+	Hs
		998665 EP300_HUMAN (1-2426): 0: 874: 55.06		PRP4K_HUMAN (172-528): 1e-40: 165: 31.77