HitPredict

Interactor 1: KAT2B (Q92831)
Histone acetyltransferase KAT2B (EC 2.3.1.48) (Histone acetyltransferase PCAF) (Histone acetylase PCAF) (Lysine acetyltransferase 2B) (P300/CBP-associated factor) (P/CAF) (Spermidine acetyltransferase KAT2B) (EC 2.3.1.57)
Gene: KAT2B

Interactor 2: FZR1 (Q9UM11)
Fizzy-related protein homolog (Fzr) (CDC20-like protein 1) (Cdh1/Hct1 homolog) (hCDH1)
Gene: FZR1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	33306668
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Acetyltransf_1~WD40
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 832 Hs			1 496
+	Hs
		903409 KAT2B_HUMAN (72-832): 0: 1128: 100.00		WDR5_HUMAN (389-496): 1.49e-26: 111: 18.35
+	Hs
		903408 KAT2A_HUMAN (63-832): 0: 1056: 73.42		WDR5_HUMAN (389-496): 1.49e-26: 111: 18.35
+	Hs
		1271467 KAT2A_HUMAN (63-832): 0: 1056: 73.42		FZR1_HUMAN (319-495): 6.65e-25: 109: 18.68
+	Mm
		903679 KAT2A_MOUSE (67-832): 0: 1044: 74.19		WDR5_MOUSE (389-496): 1.49e-26: 111: 18.35
+	Dm
		1358857 Q9VTZ1_DROME (64-832): 0: 954: 47.18		WDS_DROME (389-496): 1.28e-24: 106: 17.43
+	Hs
		631541 BRD2_HUMAN (663-830): 1.89e-35: 146: 23.37		FBXW7_HUMAN (87-424): 1.7e-71: 242: 18.68
+	Hs
		1346965 BAZ2A_HUMAN (698-826): 7.81e-38: 155: 35.66		NLE1_HUMAN (52-385): 3.28e-60: 207: 16.32
+	Hs
		1346964 BAZ2B_HUMAN (651-824): 7.98e-37: 152: 22.46		NLE1_HUMAN (52-385): 3.28e-60: 207: 16.32
+	Hs
		170444 TIF1A_HUMAN (641-827): 1.04e-38: 157: 22.22		SNR40_HUMAN (32-339): 1.33e-49: 175: 15.89
+	Hs
		1288369 BAZ2A_HUMAN (698-826): 7.81e-38: 155: 35.66		SNR40_HUMAN (32-339): 1.33e-49: 175: 15.89
+	Hs
		1288368 BAZ2B_HUMAN (651-824): 7.98e-37: 152: 22.46		SNR40_HUMAN (32-339): 1.33e-49: 175: 15.89
+	Hs
		244767 BRD4_HUMAN (680-832): 1.99e-31: 134: 22.15		SNR40_HUMAN (32-339): 1.33e-49: 175: 15.89
+	Hs
		244210 BRD4_HUMAN (680-832): 1.99e-31: 134: 22.15		WDR5_HUMAN (389-496): 1.49e-26: 111: 18.35
+	Hs
		244901 BRD4_HUMAN (680-832): 1.99e-31: 134: 22.15		TBL1R_HUMAN (98-260): 6.38e-22: 100: 13.22
+	Hs
		631433 BRD2_HUMAN (663-830): 1.89e-35: 146: 23.37		TAF5_HUMAN (232-494): 4.48e-09: 60.8: 23.02
+	Hs
		1066968 BRD3_HUMAN (672-830): 6.16e-33: 138: 22.67		TAF5_HUMAN (232-494): 4.48e-09: 60.8: 23.02
+	Hs
		1074790 BRDT_HUMAN (656-830): 3.32e-31: 133: 22.95		TAF5_HUMAN (232-494): 4.48e-09: 60.8: 23.02
+	Hs
		1017404 PB1_HUMAN (683-826): 4.92e-18: 91.8: 22.00		CDC20_HUMAN (395-494): 7.34e-10: 63: 16.67
+	Hs
		1074799 PHIP_HUMAN (683-826): 5.4e-15: 81.7: 24.49		TAF5_HUMAN (232-494): 4.48e-09: 60.8: 23.02