HitPredict

Interactor 1: RFIP2 (Q7L804)
Rab11 family-interacting protein 2 (Rab11-FIP2) (NRip11)
Gene: RAB11FIP2

Interactor 2: RFIP4 (Q86YS3)
Rab11 family-interacting protein 4 (FIP4-Rab11) (Rab11-FIP4) (Arfophilin-2)
Gene: RAB11FIP4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	12470645
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	RBD-FIP~RBD-FIP
Common GO terms	GO:0005768 - endosome GO:0031267 - small GTPase binding GO:0042803 - protein homodimerization activity GO:0043231 - intracellular membrane-bounded organelle GO:0055038 - recycling endosome membrane
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 512 Hs			1 637
+	Hs
		1295408 RFIP5_HUMAN (141-504): 7.3e-33: 134: 16.41		RFIP4_HUMAN (1-637): 1.14e-55: 201: 100.00
+	Hs
		587813 SMUF1_HUMAN (2-461): 5.63e-67: 231: 12.40		DESP_HUMAN (252-627): 3.37e-12: 72.3: 13.59
+	Hs
		436732 KPCB_HUMAN (15-226): 7.26e-42: 160: 15.11		CAR11_HUMAN (267-592): 7.35e-32: 134: 15.52
+	Hs
		1141667 SYT6_HUMAN (8-264): 4.22e-50: 180: 14.95		EEA1_HUMAN (72-476): 3.11e-09: 62.5: 8.12
+	Hs
		1122787 DOC2A_HUMAN (12-271): 4.04e-47: 170: 16.33		EEA1_HUMAN (72-476): 3.11e-09: 62.5: 8.12
+	Dm
		424690 KPC1_DROME (15-226): 8.55e-38: 149: 17.05		MYSN_DROME (66-505): 4.07e-13: 75.2: 9.66
+	Hs
		436671 KPCB_HUMAN (15-226): 7.26e-42: 160: 15.11		EEA1_HUMAN (72-476): 3.11e-09: 62.5: 8.12
+	Hs
		1141903 RFIP5_HUMAN (141-504): 7.3e-33: 134: 16.41		EEA1_HUMAN (72-476): 3.11e-09: 62.5: 8.12
+	Hs
		1410804 SYT3_HUMAN (7-139): 6.09e-24: 107: 17.22		MYH4_HUMAN (52-599): 5.55e-16: 84.5: 8.89
+	Hs
		1095554 RIMS1_HUMAN (13-127): 1.01e-12: 73.1: 23.77		LIPA1_HUMAN (237-624): 1.2e-25: 115: 16.83
+	Hs
		556949 SYT3_HUMAN (7-139): 6.09e-24: 107: 17.22		MYH7_HUMAN (156-636): 1.27e-12: 73.4: 11.34
+	Hs
		297328 DYSF_HUMAN (14-216): 1.74e-14: 78.8: 12.08		MYH3_HUMAN (52-587): 7.5e-16: 84.1: 9.28
+	Hs
		773219 RIMS1_HUMAN (13-127): 1.01e-12: 73.1: 23.77		MYH10_HUMAN (68-626): 2.43e-17: 88.7: 10.80
+	Hs
		772886 RIMS1_HUMAN (13-127): 1.01e-12: 73.1: 23.77		MYH9_HUMAN (56-470): 1.78e-10: 66.4: 9.79
+	Hs
		1288959 RIMS1_HUMAN (13-127): 1.01e-12: 73.1: 23.77		MRCKB_HUMAN (52-440): 2.03e-09: 62.9: 5.84
+	Hs
		1141745 RIMS1_HUMAN (13-127): 1.01e-12: 73.1: 23.77		EEA1_HUMAN (72-476): 3.11e-09: 62.5: 8.12
+	Hs
		276376 RIMS1_HUMAN (13-127): 1.01e-12: 73.1: 23.77		LIPA2_HUMAN (199-529): 5.2e-09: 61.5: 12.31