HitPredict

Interactor 1: H2B1H (Q93079)
Histone H2B type 1-H (H2B-clustered histone 9) (Histone H2B.j) (H2B/j)
Gene: H2BC9

Interactor 2: MRCKB (Q9Y5S2)
Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (CDC42BP-beta) (DMPK-like beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (MRCK beta) (Myotonic dystrophy protein kinase-like beta)
Gene: CDC42BPB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	30021884
Identification Methods	proximity labelling technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 126 Hs			1 1711
+	Hs
		1129870 H2B2F_HUMAN (1-126): 1.7e-55: 170: 99.21		MRCKB_HUMAN (1-1711): 0: 1556: 100.00
+	Hs
		886228 H2B1D_HUMAN (1-126): 3.03e-54: 167: 98.41		MRCKB_HUMAN (1-1711): 0: 1556: 100.00
+	Hs
		148290 H2B1J_HUMAN (1-126): 7.3e-55: 169: 97.62		CTRO_HUMAN (5-1085): 8.52e-127: 442: 24.93
+	Hs
		148194 H2B1K_HUMAN (1-126): 1.18e-54: 168: 98.41		CTRO_HUMAN (5-1085): 8.52e-127: 442: 24.93
+	Hs
		148588 H2BFS_HUMAN (1-126): 1.16e-54: 168: 96.83		CTRO_HUMAN (5-1085): 8.52e-127: 442: 24.93
+	Hs
		149215 H2B1L_HUMAN (1-126): 2.43e-53: 165: 97.62		CTRO_HUMAN (5-1085): 8.52e-127: 442: 24.93
+	Hs
		149042 H2B3B_HUMAN (1-126): 1.45e-52: 163: 96.03		CTRO_HUMAN (5-1085): 8.52e-127: 442: 24.93
+	Mm
		1169655 H2B1P_MOUSE (1-126): 3.54e-54: 167: 96.83		TAOK2_MOUSE (50-929): 2.77e-126: 429: 16.08
+	Hs
		149147 H2B1A_HUMAN (1-126): 1.15e-47: 151: 84.25		CTRO_HUMAN (5-1085): 8.52e-127: 442: 24.93
+	Hs
		1069607 H2B2E_HUMAN (1-126): 5.74e-55: 169: 98.41		STK38_HUMAN (4-421): 5.25e-119: 385: 38.77
+	Hs
		568756 H2B1H_HUMAN (1-126): 4.31e-55: 169: 100.00		KAPCA_HUMAN (48-375): 1.99e-119: 382: 34.72
+	Hs
		610760 H2B1H_HUMAN (1-126): 4.31e-55: 169: 100.00		KAPCB_HUMAN (50-375): 2.2e-119: 382: 35.52
+	Hs
		241440 H2B1K_HUMAN (1-126): 1.18e-54: 168: 98.41		KAPCA_HUMAN (48-375): 1.99e-119: 382: 34.72
+	Hs
		610687 H2B1B_HUMAN (1-126): 1.44e-54: 168: 96.83		KAPCB_HUMAN (50-375): 2.2e-119: 382: 35.52
+	Hs
		610761 H2B1A_HUMAN (1-126): 1.15e-47: 151: 84.25		KAPCB_HUMAN (50-375): 2.2e-119: 382: 35.52
+	Hs
		1087429 H2B2E_HUMAN (1-126): 5.74e-55: 169: 98.41		LATS2_HUMAN (66-375): 4.05e-70: 259: 40.34
+	Hs
		254485 H2B2E_HUMAN (1-126): 5.74e-55: 169: 98.41		ROCK2_HUMAN (362-1073): 2.09e-23: 110: 13.59