Interactor 1: SAP18 (O00422)
Histone deacetylase complex subunit SAP18 (18 kDa Sin3-associated polypeptide) (2HOR0202) (Cell growth-inhibiting gene 38 protein) (Sin3-associated polypeptide p18)
Gene: SAP18

Interactor 2: SRSF6 (Q13247)
Serine/arginine-rich splicing factor 6 (Pre-mRNA-splicing factor SRP55) (Splicing factor, arginine/serine-rich 6)
Gene: SRSF6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains RRM_1~SAP18
Common GO terms GO:0000381 - regulation of alternative mRNA splicing, via spliceosome
GO:0003723 - RNA binding
GO:0005654 - nucleoplasm
GO:0016607 - nuclear speck
GO:0048025 - negative regulation of mRNA splicing, via spliceosome
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 153
Hs

1 344
+ Hs
+ Cn

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Last updated: 15 Jul 2024