Interactor 1: ARHG8 (Q7Z628)
Neuroepithelial cell-transforming gene 1 protein (Proto-oncogene p65 Net1) (Rho guanine nucleotide exchange factor 8)
Gene: NET1
Interactor 2: RGAP1 (Q9H0H5)
Rac GTPase-activating protein 1 (Male germ cell RacGap) (MgcRacGAP) (Protein CYK4 homolog) (CYK4) (HsCYK-4)
Gene: RACGAP1
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.54 | 1.00 | 0.737 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 32203420, unassigned2213 |
| Identification Methods | affinity chromatography technology, anti tag coimmunoprecipitation |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | C1_1~RhoGEF, C1_1~SOS1_NGEF_PH |
| Common GO terms | GO:0005634 - nucleus GO:0005829 - cytosol GO:0051056 - regulation of small GTPase mediated signal transduction |
| Homologous interactions | 7 |
Homologous interactions
Color coding for hit scores 
Service provided by Combinatics, Japan
Last updated: 11Aug2025