HitPredict

Interactor 1: IF2B3 (O00425)
Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2 mRNA-binding protein 3) (IMP-3) (IGF-II mRNA-binding protein 3) (KH domain-containing protein overexpressed in cancer) (hKOC) (VICKZ family member 3)
Gene: IGF2BP3

Interactor 2: AGO1 (Q9UL18)
Protein argonaute-1 (Argonaute1) (hAgo1) (Argonaute RISC catalytic component 1) (Eukaryotic translation initiation factor 2C 1) (eIF-2C 1) (eIF2C 1) (Putative RNA-binding protein Q99)
Gene: AGO1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	17932509
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000932 - P-body GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 579 Hs			1 857
+	Mm
		1208652 IF2B3_MOUSE (1-579): 2.72e-144: 430: 96.55		AGO2_MOUSE (3-857): 0: 1213: 82.36
+	Hs
		1349167 IF2B1_HUMAN (1-579): 1.24e-135: 408: 72.02		AGO1_HUMAN (1-857): 0: 1222: 100.00
+	Mm
		291672 IF2B1_MOUSE (1-577): 5.34e-136: 409: 71.06		AGO2_MOUSE (3-857): 0: 1213: 82.36
+	Hs
		1349166 IF2B1_HUMAN (1-579): 1.24e-135: 408: 72.02		AGO2_HUMAN (19-857): 0: 1206: 83.43
+	Hs
		1336278 IF2B1_HUMAN (1-579): 1.24e-135: 408: 72.02		AGO4_HUMAN (9-857): 0: 1167: 83.04
+	Hs
		1072207 PCBP2_HUMAN (193-484): 7.41e-30: 122: 19.05		AGO1_HUMAN (1-857): 0: 1222: 100.00
+	Ce
		108534 Q21605_CAEEL (172-559): 2.02e-65: 230: 24.79		G5EGR6_CAEEL (21-857): 0: 1109: 66.36
+	Hs
		1072205 PCBP2_HUMAN (193-484): 7.41e-30: 122: 19.05		AGO2_HUMAN (19-857): 0: 1206: 83.43
+	Hs
		1356726 IF2B2_HUMAN (79-477): 8.15e-20: 95.1: 15.50		AGO1_HUMAN (1-857): 0: 1222: 100.00
+	Hs
		1294277 FUBP3_HUMAN (189-414): 5.52e-18: 89.3: 14.17		AGO1_HUMAN (1-857): 0: 1222: 100.00
+	Mm
		1130844 IF2B2_MOUSE (79-477): 2.08e-20: 97: 15.76		AGO2_MOUSE (3-857): 0: 1213: 82.36
+	Hs
		1356637 IF2B2_HUMAN (79-477): 8.15e-20: 95.1: 15.50		AGO2_HUMAN (19-857): 0: 1206: 83.43
+	Hs
		1294275 FUBP3_HUMAN (189-414): 5.52e-18: 89.3: 14.17		AGO2_HUMAN (19-857): 0: 1206: 83.43
+	Mm
		1208650 Q99LF8_MOUSE (73-346): 4.23e-13: 74.3: 9.39		AGO2_MOUSE (3-857): 0: 1213: 82.36
+	Mm
		665763 PABP1_MOUSE (74-346): 9.49e-12: 69.6: 8.30		AGO2_MOUSE (3-857): 0: 1213: 82.36
+	Hs
		1294256 FUBP3_HUMAN (189-414): 5.52e-18: 89.3: 14.17		AGO3_HUMAN (1-857): 0: 1189: 83.83
+	Hs
		516735 PABP1_HUMAN (74-346): 1.06e-11: 69.6: 8.30		AGO2_HUMAN (19-857): 0: 1206: 83.43
+	Hs
		516695 PABP1_HUMAN (74-346): 1.06e-11: 69.6: 8.30		AGO3_HUMAN (1-857): 0: 1189: 83.83
+	Hs
		1031470 PABP4_HUMAN (73-346): 8e-14: 76.6: 9.03		AGO4_HUMAN (9-857): 0: 1167: 83.04
+	Hs
		516701 PABP1_HUMAN (74-346): 1.06e-11: 69.6: 8.30		AGO4_HUMAN (9-857): 0: 1167: 83.04