Protein: HUL5
E3 ubiquitin-protein ligase HUL5 (EC 2.3.2.26)

Gene: HUL5
Organism: Saccharomyces cerevisiae S288C
Interactions: 31
UniProt ID: P53119

Gene Ontology (top 5):
GO:0000209 - protein polyubiquitination
GO:0000502 - proteasome complex
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

509651

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

20

Small-scale

0.618

High

585717

UBC4
Ubiquitin-conjugating enzyme E2 4

1

20

Small-scale

0.618

High

585755

UBC5
Ubiquitin-conjugating enzyme E2-16 kDa

1

20

Small-scale

0.618

High

917352

PRS8
26S proteasome regulatory subunit 8 homolog

2

19

High-throughput

0.601

High

755269

NUF2
Kinetochore protein NUF2

1

2

High-throughput

0.541

High

449152

CALM
Calmodulin

1

13

High-throughput

0.536

High

740193

RPN2
26S proteasome regulatory subunit RPN2

1

9

Small-scale

0.501

High

806774

RPN10
26S proteasome regulatory subunit RPN10

1

9

Small-scale

0.501

High

865507

PTK2
Serine/threonine-protein kinase PTK2/STK2

1

12

High-throughput

0.501

High

633175

MAK11
Protein MAK11

1

13

High-throughput

0.489

High

779821

OAF3
Oleate activated transcription factor 3

1

0

High-throughput

0.486

High

579765

HSC82
ATP-dependent molecular chaperone HSC82

1

18

High-throughput

0.479

High

645190

PSB4
Proteasome subunit beta type-4

1

20

Small-scale

0.479

High

661545

PSA2
Proteasome subunit alpha type-2

1

18

High-throughput

0.479

High

679893

CDC48
Cell division control protein 48

1

5

High-throughput

0.479

High

707688

TF2B
Transcription initiation factor IIB

1

4

High-throughput

0.479

High

741015

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

10

High-throughput

0.479

High

850107

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

18

Small-scale

0.479

High

917351

APJ1
J domain-containing protein APJ1

1

11

High-throughput

0.479

High

917354

RPN5
26S proteasome regulatory subunit RPN5

1

7

Small-scale

0.479

High

917350

VIR
Protein virilizer

1

0

High-throughput

0.458

High

524605

HSP71
Heat shock protein SSA1

1

13

High-throughput

0.445

High

527218

HSP72
Heat shock protein SSA2

1

13

High-throughput

0.445

High

545617

SSB1
Ribosome-associated molecular chaperone SSB1

1

13

High-throughput

0.445

High

742009

HSP7F
Heat shock protein homolog SSE1

1

20

High-throughput

0.445

High

804309

SSZ1
Ribosome-associated complex subunit SSZ1

1

9

High-throughput

0.445

High

819305

SSB2
Ribosome-associated molecular chaperone SSB2

1

13

High-throughput

0.445

High

850322

UBP6
Ubiquitin carboxyl-terminal hydrolase 6

1

20

Small-scale

0.445

High

865009

TCPQ
T-complex protein 1 subunit theta

1

14

High-throughput

0.445

High

810991

TCPD
T-complex protein 1 subunit delta

1

17

High-throughput

0.407

High

917353

PML39
Pre-mRNA leakage protein 39

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025