HitPredict

Interactor 1: BIRC7 (Q96CA5)
Baculoviral IAP repeat-containing protein 7 (EC 2.3.2.27) (Kidney inhibitor of apoptosis protein) (KIAP) (Livin) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (RING finger protein 50) (RING-type E3 ubiquitin transferase BIRC7) [Cleaved into: Baculoviral IAP repeat-containing protein 7 30kDa subunit (Truncated livin) (p30-Livin) (tLivin)]
Gene: BIRC7

Interactor 2: BIRC7 (Q96CA5)
Baculoviral IAP repeat-containing protein 7 (EC 2.3.2.27) (Kidney inhibitor of apoptosis protein) (KIAP) (Livin) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (RING finger protein 50) (RING-type E3 ubiquitin transferase BIRC7) [Cleaved into: Baculoviral IAP repeat-containing protein 7 30kDa subunit (Truncated livin) (p30-Livin) (tLivin)]
Gene: BIRC7

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.65 1.00 0.808

The method score is based on:

Property Details
Experiments 22902369, 21113135
Identification Methods enzymatic study, pull down, two hybrid, molecular sieving
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains BIR~BIR, BIR~zf-C3HC4_3, zf-C3HC4_3~zf-C3HC4_3
Common GO terms GO:0002088 - lens development in camera-type eye
GO:0004842 - ubiquitin-protein transferase activity
GO:0004869 - cysteine-type endopeptidase inhibitor activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 19 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 298
Hs

1 298
+ Hs
+ Hs
+ Mm
+ Hs
+ Zm
+ Hs
+ Hs
+ At
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Mm
+ Dm
+ Dr
+ Hs
+ Dr
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024