HitPredict

Interactor 1: LRRT3 (Q86VH5)
Leucine-rich repeat transmembrane neuronal protein 3
Gene: LRRTM3

Interactor 2: GPC6 (Q9Y625)
Glypican-6 [Cleaved into: Secreted glypican-6]
Gene: GPC6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 581 Hs			1 555
+	Hs
		1290424 LRRT4_HUMAN (1-572): 6.95e-123: 376: 59.34		GPC6_HUMAN (1-555): 0: 834: 100.00
+	Hs
		283704 LRRT3_HUMAN (1-581): 5.99e-148: 440: 100.00		GPC4_HUMAN (26-555): 0: 759: 65.60
+	Hs
		1288341 LRRT1_HUMAN (10-513): 3.97e-101: 317: 44.81		GPC6_HUMAN (1-555): 0: 834: 100.00
+	Hs
		283703 LRRT4_HUMAN (1-572): 6.95e-123: 376: 59.34		GPC4_HUMAN (26-555): 0: 759: 65.60
+	Rn
		76713 LRRT4_RAT (1-572): 3.4e-121: 372: 59.17		Q642B0_RAT (26-555): 0: 754: 66.60
+	Hs
		762349 LRRT3_HUMAN (1-581): 5.99e-148: 440: 100.00		GPC1_HUMAN (21-506): 0: 645: 49.59
+	Hs
		283702 LRRT1_HUMAN (10-513): 3.97e-101: 317: 44.81		GPC4_HUMAN (26-555): 0: 759: 65.60
+	Hs
		762348 LRRT4_HUMAN (1-572): 6.95e-123: 376: 59.34		GPC1_HUMAN (21-506): 0: 645: 49.59
+	Hs
		906311 LRRT3_HUMAN (1-581): 5.99e-148: 440: 100.00		GPC3_HUMAN (1-504): 0: 568: 27.18
+	Hs
		762347 LRRT1_HUMAN (10-513): 3.97e-101: 317: 44.81		GPC1_HUMAN (21-506): 0: 645: 49.59
+	Hs
		906310 LRRT4_HUMAN (1-572): 6.95e-123: 376: 59.34		GPC3_HUMAN (1-504): 0: 568: 27.18
+	Hs
		212898 LRRT2_HUMAN (1-513): 3.31e-89: 286: 44.21		GPC3_HUMAN (1-504): 0: 568: 27.18
+	Dm
		663794 SLIT_DROME (160-397): 2.37e-42: 165: 25.31		DALY_DROME (30-550): 4.78e-139: 418: 22.16