HitPredict

Interactor 1: GPC4 (O75487)
Glypican-4 (K-glypican) [Cleaved into: Secreted glypican-4]
Gene: GPC4

Interactor 2: LRRT3 (Q86VH5)
Leucine-rich repeat transmembrane neuronal protein 3
Gene: LRRTM3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	33961781, unassigned3799
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0098978 - glutamatergic synapse GO:1905606 - regulation of presynapse assembly
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 556 Hs			1 581
+	Hs
		1290442 GPC6_HUMAN (23-556): 0: 748: 64.79		LRRT3_HUMAN (1-581): 5.99e-148: 440: 100.00
+	Hs
		283703 GPC4_HUMAN (1-556): 0: 806: 100.00		LRRT4_HUMAN (1-572): 6.95e-123: 376: 59.34
+	Rn
		76713 Q642B0_RAT (24-556): 0: 774: 93.82		LRRT4_RAT (1-572): 3.4e-121: 372: 59.17
+	Hs
		1290424 GPC6_HUMAN (23-556): 0: 748: 64.79		LRRT4_HUMAN (1-572): 6.95e-123: 376: 59.34
+	Hs
		283702 GPC4_HUMAN (1-556): 0: 806: 100.00		LRRT1_HUMAN (10-513): 3.97e-101: 317: 44.81
+	Hs
		762349 GPC1_HUMAN (23-507): 0: 646: 45.57		LRRT3_HUMAN (1-581): 5.99e-148: 440: 100.00
+	Hs
		1288341 GPC6_HUMAN (23-556): 0: 748: 64.79		LRRT1_HUMAN (10-513): 3.97e-101: 317: 44.81
+	Hs
		762348 GPC1_HUMAN (23-507): 0: 646: 45.57		LRRT4_HUMAN (1-572): 6.95e-123: 376: 59.34
+	Hs
		906311 GPC3_HUMAN (6-501): 0: 558: 25.96		LRRT3_HUMAN (1-581): 5.99e-148: 440: 100.00
+	Hs
		762347 GPC1_HUMAN (23-507): 0: 646: 45.57		LRRT1_HUMAN (10-513): 3.97e-101: 317: 44.81
+	Hs
		906310 GPC3_HUMAN (6-501): 0: 558: 25.96		LRRT4_HUMAN (1-572): 6.95e-123: 376: 59.34
+	Hs
		212898 GPC3_HUMAN (6-501): 0: 558: 25.96		LRRT2_HUMAN (1-513): 3.31e-89: 286: 44.21
+	Dm
		663794 DALY_DROME (17-458): 2.49e-133: 403: 22.11		SLIT_DROME (160-397): 2.37e-42: 165: 25.31