HitPredict

Interactor 1: DC2I2 (Q96EX3)
Cytoplasmic dynein 2 intermediate chain 2 (Dynein 2 intermediate chain 2) (WD repeat-containing protein 34)
Gene: DYNC2I2

Interactor 2: TRAF6 (Q9Y4K3)
TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (Interleukin-1 signal transducer) (RING finger protein 85) (RING-type E3 ubiquitin transferase TRAF6)
Gene: TRAF6

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.573

Property	Details
Experiments	19521662
Identification Methods	affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 536 Hs			1 522
+	Hs
		1151063 Q6FHQ0_HUMAN (105-535): 1.14e-75: 247: 14.16		TRAF6_HUMAN (1-522): 1.12e-151: 445: 100.00
+	Hs
		903641 WDR5_HUMAN (2-341): 1.79e-50: 177: 11.65		TRAF6_HUMAN (1-522): 1.12e-151: 445: 100.00
+	Hs
		903186 WDR5_HUMAN (2-341): 1.79e-50: 177: 11.65		TRAF3_HUMAN (19-501): 9.91e-86: 277: 22.18
+	Hs
		1020851 FBXW7_HUMAN (37-294): 3.57e-21: 99.3: 11.63		TRAF2_HUMAN (40-500): 7.2e-101: 314: 25.85
+	Hs
		148087 DC1I1_HUMAN (11-536): 2.11e-70: 239: 18.44		TRI58_HUMAN (62-403): 4.42e-43: 161: 11.67
+	Hs
		1083377 RBBP7_HUMAN (105-535): 1.14e-75: 247: 14.16		TRI31_HUMAN (58-334): 3.02e-35: 138: 15.00
+	Hs
		245603 TBL1X_HUMAN (79-424): 4.56e-50: 182: 9.68		TRI25_HUMAN (63-370): 4.93e-45: 169: 18.61
+	Hs
		997722 RBBP4_HUMAN (320-526): 6.81e-34: 134: 15.81		TRI25_HUMAN (63-370): 4.93e-45: 169: 18.61
+	Mm
		250605 LIS1_MOUSE (262-536): 3.44e-63: 214: 11.63		LNX1_MOUSE (51-183): 2.1e-11: 68.7: 19.55
+	Hs
		793013 LIS1_HUMAN (262-536): 4.91e-63: 213: 11.63		LNX1_HUMAN (58-183): 2.59e-11: 68.3: 19.84
+	Hs
		1052726 FBXW7_HUMAN (37-294): 3.57e-21: 99.3: 11.63		TRI25_HUMAN (63-370): 4.93e-45: 169: 18.61
+	Hs
		585027 FBXW7_HUMAN (37-294): 3.57e-21: 99.3: 11.63		RO52_HUMAN (64-403): 5.77e-45: 166: 14.97
+	Hs
		1019346 FBXW7_HUMAN (37-294): 3.57e-21: 99.3: 11.63		TRI26_HUMAN (61-410): 2.85e-38: 149: 14.59
+	Hs
		301694 COPA_HUMAN (3-235): 1.76e-10: 65.8: 5.58		TRI37_HUMAN (56-501): 7.36e-43: 165: 13.89
+	Hs
		863547 COPA_HUMAN (3-235): 1.76e-10: 65.8: 5.58		TRI31_HUMAN (58-334): 3.02e-35: 138: 15.00
+	Hs
		863498 COPA_HUMAN (3-235): 1.76e-10: 65.8: 5.58		LNX1_HUMAN (58-183): 2.59e-11: 68.3: 19.84