Protein: TRI52
E3 ubiquitin-protein ligase TRIM52 (EC 2.3.2.27) (RING finger protein 102) (Tripartite motif-containing protein 52)

Gene: TRI52, TRIM52
Organism: Homo sapiens
Interactions: 132
UniProt ID: Q96A61

Gene Ontology (top 5):
GO:0003713 - transcription coactivator activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0008270 - zinc ion binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1357715

TRI41
E3 ubiquitin-protein ligase TRIM41

2

19

High-throughput

0.817

High

1382559

RN114
E3 ubiquitin-protein ligase RNF114

1

20

High-throughput

0.698

High

180891

TIF1A
Transcription intermediary factor 1-alpha

1

19

High-throughput

0.691

High

714332

PML
Protein PML

1

20

High-throughput

0.691

High

1382551

TRI33
E3 ubiquitin-protein ligase TRIM33

1

18

High-throughput

0.691

High

776993

PPM1A
Protein phosphatase 1A

2

1

Small-scale

0.584

High

1361822

RSPH1
Radial spoke head 1 homolog

1

2

High-throughput

0.541

High

1382521

RN126
E3 ubiquitin-protein ligase RNF126

1

6

High-throughput

0.541

High

861711

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

3

High-throughput

0.536

High

67695

RHG32
Rho GTPase-activating protein 32

1

7

High-throughput

0.536

High

74050

MYO9A
Unconventional myosin-IXa

1

10

High-throughput

0.536

High

159013

ZN195
Zinc finger protein 195

1

6

High-throughput

0.536

High

165067

RPC1
DNA-directed RNA polymerase III subunit RPC1

1

2

High-throughput

0.536

High

176415

ZBTB5
Zinc finger and BTB domain-containing protein 5

1

20

High-throughput

0.536

High

177034

CE290
Centrosomal protein of 290 kDa

1

20

High-throughput

0.536

High

213221

CP110
Centriolar coiled-coil protein of 110 kDa

1

2

High-throughput

0.536

High

278400

NCOR1
Nuclear receptor corepressor 1

1

13

High-throughput

0.536

High

282896

Z324A
Zinc finger protein 324A

1

20

High-throughput

0.536

High

315850

RECQ4
ATP-dependent DNA helicase Q4

1

14

High-throughput

0.536

High

331784

MTMR5
Myotubularin-related protein 5

1

4

High-throughput

0.536

High

334071

SMC2
Structural maintenance of chromosomes protein 2

1

5

High-throughput

0.536

High

340016

RPA1
DNA-directed RNA polymerase I subunit RPA1

1

2

High-throughput

0.536

High

340200

PCNT
Pericentrin

1

18

High-throughput

0.536

High

451552

CENPB
Major centromere autoantigen B

1

4

High-throughput

0.536

High

542609

TOP2A
DNA topoisomerase 2-alpha

1

1

High-throughput

0.536

High

723040

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

2

High-throughput

0.536

High

777311

AHR
Aryl hydrocarbon receptor

1

8

High-throughput

0.536

High

903082

DNA2
DNA replication ATP-dependent helicase/nuclease DNA2

1

4

High-throughput

0.536

High

923713

SMTN
Smoothelin

1

7

High-throughput

0.536

High

948215

ZN445
Zinc finger protein 445

1

7

High-throughput

0.536

High

1039548

TOP2B
DNA topoisomerase 2-beta

1

1

High-throughput

0.536

High

1106221

MYO9B
Unconventional myosin-IXb

1

8

High-throughput

0.536

High

1111471

IQGA2
Ras GTPase-activating-like protein IQGAP2

1

10

High-throughput

0.536

High

1112948

CUL2
Cullin-2

1

20

High-throughput

0.536

High

1140125

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

1

High-throughput

0.536

High

1191459

GRDN
Girdin

1

15

High-throughput

0.536

High

1198313

TIGD5
Tigger transposable element-derived protein 5

1

4

High-throughput

0.536

High

1217491

CE350
Centrosome-associated protein 350

1

14

High-throughput

0.536

High

1228447

FTM
Protein fantom

1

18

High-throughput

0.536

High

1232064

TTLL5
Tubulin polyglutamylase TTLL5

1

1

High-throughput

0.536

High

1246914

RICTR
Rapamycin-insensitive companion of mTOR

1

1

High-throughput

0.536

High

1253917

FA83H
Protein FAM83H

1

1

High-throughput

0.536

High

1275947

SETX
Probable helicase senataxin

1

4

High-throughput

0.536

High

1290463

IQGA3
Ras GTPase-activating-like protein IQGAP3

1

9

High-throughput

0.536

High

1291557

HOOK3
Protein Hook homolog 3

1

14

High-throughput

0.536

High

1309471

CEP97
Centrosomal protein of 97 kDa

1

3

High-throughput

0.536

High

1310101

MGAP
MAX gene-associated protein

1

2

High-throughput

0.536

High

1316848

ASPM
Abnormal spindle-like microcephaly-associated protein

1

15

High-throughput

0.536

High

1322416

SPICE
Spindle and centriole-associated protein 1

1

1

High-throughput

0.536

High

1323119

CCAR2
Cell cycle and apoptosis regulator protein 2

1

1

High-throughput

0.536

High

1324985

ASCC3
Activating signal cointegrator 1 complex subunit 3

1

11

High-throughput

0.536

High

1350164

ALMS1
Centrosome-associated protein ALMS1

1

2

High-throughput

0.536

High

1365952

APBP2
Amyloid protein-binding protein 2

1

5

High-throughput

0.536

High

1371046

ARHG2
Rho guanine nucleotide exchange factor 2

1

4

High-throughput

0.536

High

1380937

LMBL2
Lethal(3)malignant brain tumor-like protein 2

1

1

High-throughput

0.536

High

1382513

THA11
THAP domain-containing protein 11

1

1

High-throughput

0.536

High

1382515

SAM11
Sterile alpha motif domain-containing protein 11

1

2

High-throughput

0.536

High

1382516

CK5P2
CDK5 regulatory subunit-associated protein 2

1

20

High-throughput

0.536

High

1382518

TEP1
Telomerase protein component 1

1

8

High-throughput

0.536

High

1382520

KLDC3
Kelch domain-containing protein 3

1

4

High-throughput

0.536

High

1382523

FANCJ
Fanconi anemia group J protein

1

1

High-throughput

0.536

High

1382524

PCGF6
Polycomb group RING finger protein 6

1

19

High-throughput

0.536

High

1382528

KLC2
Kinesin light chain 2

1

6

High-throughput

0.536

High

1382529

ZN644
Zinc finger protein 644

1

18

High-throughput

0.536

High

1382533

WDR76
WD repeat-containing protein 76

1

3

High-throughput

0.536

High

1382535

RPA2
DNA-directed RNA polymerase I subunit RPA2

1

2

High-throughput

0.536

High

1382537

PKHA5
Pleckstrin homology domain-containing family A member 5

1

10

High-throughput

0.536

High

1382539

MYO5C
Unconventional myosin-Vc

1

3

High-throughput

0.536

High

1382540

DISC1
Disrupted in schizophrenia 1 protein

1

3

High-throughput

0.536

High

1382545

RTEL1
Regulator of telomere elongation helicase 1

1

1

High-throughput

0.536

High

1382546

SI1L2
Signal-induced proliferation-associated 1-like protein 2

1

2

High-throughput

0.536

High

1382547

NYNRI
Protein NYNRIN

1

5

High-throughput

0.536

High

1382549

MTUS1
Microtubule-associated tumor suppressor 1

1

18

High-throughput

0.536

High

1382550

CP131
Centrosomal protein of 131 kDa

1

11

High-throughput

0.536

High

1382552

AGAP1
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1

1

3

High-throughput

0.536

High

1382553

PZRN3
E3 ubiquitin-protein ligase PDZRN3

1

12

High-throughput

0.536

High

1382554

CE164
Centrosomal protein of 164 kDa

1

14

High-throughput

0.536

High

1382555

INVS
Inversin

1

5

High-throughput

0.536

High

1382557

TRRAP
Transformation/transcription domain-associated protein

1

4

High-throughput

0.536

High

1382558

MYO5A
Unconventional myosin-Va

1

4

High-throughput

0.536

High

60770

MEIOC
Meiosis-specific coiled-coil domain-containing protein MEIOC

1

0

High-throughput

0.513

High

217172

MS18B
Protein Mis18-beta

1

0

High-throughput

0.513

High

273358

NPHP4
Nephrocystin-4

1

0

High-throughput

0.513

High

316422

RMP
Unconventional prefoldin RPB5 interactor 1

1

0

High-throughput

0.513

High

342005

CEP43
Centrosomal protein 43

1

0

High-throughput

0.513

High

351146

ECD
Protein ecdysoneless homolog

1

0

High-throughput

0.513

High

904354

BRCA2
Breast cancer type 2 susceptibility protein

1

0

High-throughput

0.513

High

912209

RPB11
DNA-directed RNA polymerase II subunit RPB11-a

1

0

High-throughput

0.513

High

1086512

TROAP
Tastin

1

0

High-throughput

0.513

High

1179184

CTC1
CST complex subunit CTC1

1

0

High-throughput

0.513

High

1193454

CCD14
Coiled-coil domain-containing protein 14

1

0

High-throughput

0.513

High

1211271

SNPC4
snRNA-activating protein complex subunit 4

1

0

High-throughput

0.513

High

1218205

ZN318
Zinc finger protein 318

1

0

High-throughput

0.513

High

1233777

CNDH2
Condensin-2 complex subunit H2

1

0

High-throughput

0.513

High

1272246

MCM10
Protein MCM10 homolog

1

0

High-throughput

0.513

High

1286643

TEDC1
Tubulin epsilon and delta complex protein 1

1

0

High-throughput

0.513

High

1293732

CNDG2
Condensin-2 complex subunit G2

1

0

High-throughput

0.513

High

1382514

SENP5
Sentrin-specific protease 5

1

0

High-throughput

0.513

High

1382519

SIN1
Target of rapamycin complex 2 subunit MAPKAP1

1

0

High-throughput

0.513

High

1382522

TALD3
Protein TALPID3

1

0

High-throughput

0.513

High

1382525

WDR11
WD repeat-containing protein 11

1

0

High-throughput

0.513

High

1382526

CE295
Centrosomal protein of 295 kDa

1

0

High-throughput

0.513

High

1382530

STN1
CST complex subunit STN1

1

0

High-throughput

0.513

High

1382532

YYAP1
YY1-associated protein 1

1

0

High-throughput

0.513

High

1382534

MARH7
E3 ubiquitin-protein ligase MARCHF7

1

0

High-throughput

0.513

High

1382536

NJMU
Protein Njmu-R1

1

0

High-throughput

0.513

High

1382541

PDRG1
p53 and DNA damage-regulated protein 1

1

0

High-throughput

0.513

High

1382542

INT7
Integrator complex subunit 7

1

0

High-throughput

0.513

High

1382543

RPC5
DNA-directed RNA polymerase III subunit RPC5

1

0

High-throughput

0.513

High

1382544

BCD1
Box C/D snoRNA protein 1

1

0

High-throughput

0.513

High

1382556

UTP11
Probable U3 small nucleolar RNA-associated protein 11

1

0

High-throughput

0.513

High

1382561

TSSC4
U5 small nuclear ribonucleoprotein TSSC4

1

0

High-throughput

0.513

High

422808

A4
Amyloid-beta precursor protein

1

8

High-throughput

0.501

High

63773

KRBA1
Protein KRBA1

1

1

High-throughput

0.489

High

1130712

DIP2A
Disco-interacting protein 2 homolog A

1

4

High-throughput

0.489

High

1237911

PHLB3
Pleckstrin homology-like domain family B member 3

1

9

High-throughput

0.489

High

1243842

CTR9
RNA polymerase-associated protein CTR9 homolog

1

3

High-throughput

0.489

High

1258159

UBP54
Ubiquitin carboxyl-terminal hydrolase 54

1

1

High-throughput

0.489

High

1311824

DHX40
Probable ATP-dependent RNA helicase DHX40

1

7

High-throughput

0.489

High

1382517

MA7D2
MAP7 domain-containing protein 2

1

13

High-throughput

0.489

High

1382527

TANC1
Protein TANC1

1

7

High-throughput

0.489

High

1382531

YTDC2
3'-5' RNA helicase YTHDC2

1

7

High-throughput

0.489

High

1382538

ALG13
UDP-N-acetylglucosamine transferase subunit ALG13

1

6

High-throughput

0.489

High

1382548

TASOR
Protein TASOR

1

1

High-throughput

0.489

High

1382560

TF3C3
General transcription factor 3C polypeptide 3

1

4

High-throughput

0.489

High

567462

TCTP
Translationally-controlled tumor protein

1

1

High-throughput

0.479

High

1135226

Q149M6
Exophilin 5

1

3

High-throughput

0.437

High

1337861

EXPH5
Exophilin-5

1

3

High-throughput

0.407

High

1085799

TF3C1
General transcription factor 3C polypeptide 1

1

0

High-throughput

0.279

Low

1216581

PR14L
Protein PRR14L

1

0

High-throughput

0.279

Low

1225961

F91A1
Protein FAM91A1

1

0

High-throughput

0.279

Low

1240391

M18BP
Mis18-binding protein 1

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025