HitPredict

Interactor 1: TAXB1 (Q86VP1)
Tax1-binding protein 1 (TRAF6-binding protein)
Gene: TAX1BP1

Interactor 2: NEMO (Q9Y6K9)
NF-kappa-B essential modulator (NEMO) (FIP-3) (IkB kinase-associated protein 1) (IKKAP1) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (I-kappa-B kinase subunit gamma) (IKK-gamma) (IKKG) (IkB kinase subunit gamma) (NF-kappa-B essential modifier)
Gene: IKBKG

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	21988832
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0006915 - apoptotic process GO:0008270 - zinc ion binding GO:0035591 - signaling adaptor activity and 1 others more... GO:0045087 - innate immune response
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 789 Hs			1 419
+	Hs
		1290930 TAXB1_HUMAN (1-789): 1.18e-82: 282: 100.00		OPTN_HUMAN (67-418): 2.8e-38: 147: 27.25
+	Hs
		1291024 TAXB1_HUMAN (1-789): 1.18e-82: 282: 100.00		MRCKB_HUMAN (39-356): 2.86e-10: 64.7: 13.60
+	Hs
		1095869 CACO2_HUMAN (7-329): 3.58e-34: 138: 27.60		NEMO_HUMAN (1-419): 1.12e-52: 183: 100.00
+	Hs
		1095747 CACO2_HUMAN (7-329): 3.58e-34: 138: 27.60		OPTN_HUMAN (67-418): 2.8e-38: 147: 27.25
+	Hs
		1217526 MRCKA_HUMAN (76-763): 1.03e-52: 201: 12.52		MRCKA_HUMAN (32-363): 1.19e-13: 75.1: 15.89
+	Hs
		1217577 MRCKA_HUMAN (76-763): 1.03e-52: 201: 12.52		MRCKB_HUMAN (39-356): 2.86e-10: 64.7: 13.60
+	Rn
		236530 MRCKA_RAT (76-763): 2.8e-52: 199: 12.66		MRCKB_RAT (45-355): 2.09e-10: 65: 14.56
+	Rn
		236526 MRCKA_RAT (76-763): 2.8e-52: 199: 12.66		MRCKA_RAT (77-391): 2.3e-09: 61.9: 16.30
+	Hs
		563026 MYH6_HUMAN (47-756): 9.84e-24: 110: 9.07		OPTN_HUMAN (67-418): 2.8e-38: 147: 27.25
+	Hs
		587642 CACO2_HUMAN (7-329): 3.58e-34: 138: 27.60		DESP_HUMAN (45-363): 7.36e-21: 97.8: 15.84
+	Hs
		772776 CACO2_HUMAN (7-329): 3.58e-34: 138: 27.60		MYH9_HUMAN (11-402): 4.52e-11: 67.3: 9.93
+	Hs
		773172 CACO2_HUMAN (7-329): 3.58e-34: 138: 27.60		MYH10_HUMAN (27-387): 1.17e-10: 65.8: 14.09
+	Hs
		563008 CACO2_HUMAN (7-329): 3.58e-34: 138: 27.60		MYH6_HUMAN (4-395): 1.41e-09: 62.3: 11.48
+	Hs
		1095736 CACO2_HUMAN (7-329): 3.58e-34: 138: 27.60		MY18A_HUMAN (10-390): 4.25e-09: 60.8: 15.89
+	Hs
		156919 CTRO_HUMAN (96-665): 1.87e-20: 99.6: 11.44		DESP_HUMAN (45-363): 7.36e-21: 97.8: 15.84
+	Hs
		556973 MYH4_HUMAN (82-777): 1.52e-24: 112: 11.35		MYH7_HUMAN (26-376): 1.59e-09: 62.3: 13.24
+	Hs
		563081 MYH4_HUMAN (82-777): 1.52e-24: 112: 11.35		MYH8_HUMAN (22-392): 1.72e-09: 62.3: 11.87
+	Hs
		562992 MYH6_HUMAN (47-756): 9.84e-24: 110: 9.07		MYH6_HUMAN (4-395): 1.41e-09: 62.3: 11.48
+	Hs
		157020 CTRO_HUMAN (96-665): 1.87e-20: 99.6: 11.44		MYH9_HUMAN (11-402): 4.52e-11: 67.3: 9.93
+	Hs
		157021 CTRO_HUMAN (96-665): 1.87e-20: 99.6: 11.44		MYH10_HUMAN (27-387): 1.17e-10: 65.8: 14.09