HitPredict

Interactor 1: MYH6 (P13533)
Myosin-6 (Myosin heavy chain 6) (Myosin heavy chain, cardiac muscle alpha isoform) (MyHC-alpha)
Gene: MYH6

Interactor 2: CACO2 (Q13137)
Calcium-binding and coiled-coil domain-containing protein 2 (Antigen nuclear dot 52 kDa protein) (Nuclear domain 10 protein NDP52) (Nuclear domain 10 protein 52) (Nuclear dot protein 52)
Gene: CALCOCO2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	29187741
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1939 Hs			1 446
+	Hs
		563036 MYH6_HUMAN (1-1939): 0: 1175: 100.00		CACO1_HUMAN (23-434): 2.24e-32: 132: 19.36
+	Hs
		562992 MYH6_HUMAN (1-1939): 0: 1175: 100.00		MYH6_HUMAN (74-439): 4.32e-10: 64.4: 11.26
+	Hs
		535921 MYH6_HUMAN (1-1939): 0: 1175: 100.00		MYH3_HUMAN (75-437): 1e-09: 63.2: 9.34
+	Rn
		386940 MYH6_RAT (1-1939): 0: 1174: 96.91		MYH6_RAT (80-439): 2.97e-09: 61.7: 11.83
+	Hs
		772776 MYH9_HUMAN (27-1928): 0: 1013: 40.02		CACO2_HUMAN (1-446): 2.19e-63: 213: 100.00
+	Hs
		772658 MYH9_HUMAN (27-1928): 0: 1013: 40.02		EPS15_HUMAN (133-433): 1.44e-27: 117: 17.30
+	Hs
		772645 MYH9_HUMAN (27-1928): 0: 1013: 40.02		MYH10_HUMAN (75-437): 6.01e-11: 67.1: 13.17
+	Hs
		772935 MYH9_HUMAN (27-1928): 0: 1013: 40.02		MY18A_HUMAN (108-352): 6.96e-11: 66.7: 14.44
+	Hs
		556902 MYH9_HUMAN (27-1928): 0: 1013: 40.02		MYH7_HUMAN (80-437): 4.47e-10: 64.4: 11.41
+	Hs
		772647 MYH9_HUMAN (27-1928): 0: 1013: 40.02		MYH11_HUMAN (81-361): 3.77e-09: 61.3: 13.68
+	Hs
		772644 MYH9_HUMAN (27-1928): 0: 1013: 40.02		MYH9_HUMAN (144-345): 7.97e-09: 60.2: 15.05
+	Hs
		773172 MYH10_HUMAN (955-1939): 3.47e-62: 238: 19.37		CACO2_HUMAN (1-446): 2.19e-63: 213: 100.00
+	Hs
		773110 MYH10_HUMAN (955-1939): 3.47e-62: 238: 19.37		MYH10_HUMAN (75-437): 6.01e-11: 67.1: 13.17
+	Mm
		1037835 MYH6_MOUSE (1041-1939): 6.16e-63: 241: 17.69		MYH1_MOUSE (99-416): 6.17e-10: 63.6: 9.40
+	Mm
		1037830 MYH6_MOUSE (1041-1939): 6.16e-63: 241: 17.69		MYH6_MOUSE (80-439): 1.42e-09: 62.4: 11.83
+	Mm
		563088 MYH6_MOUSE (1041-1939): 6.16e-63: 241: 17.69		MYH8_MOUSE (75-437): 1.66e-09: 62.4: 7.69
+	Hs
		773112 MYH10_HUMAN (955-1939): 3.47e-62: 238: 19.37		MYH11_HUMAN (81-361): 3.77e-09: 61.3: 13.68
+	Hs
		556892 MYH7_HUMAN (960-1938): 3.21e-60: 231: 16.67		MYH7_HUMAN (80-437): 4.47e-10: 64.4: 11.41