Interactor 1: FBXW8 (Q8BIA4)
F-box/WD repeat-containing protein 8 (F-box and WD-40 domain-containing protein 8)
Gene: FBXW8
Interactor 2: PRKN (Q9WVS6)
E3 ubiquitin-protein ligase parkin (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase)
Gene: PRKN
Species: Mus musculus
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25790475 |
| Identification Methods | affinity chromatography technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | F-box-like~ubiquitin |
| Common GO terms | GO:0005829 - cytosol GO:0006511 - ubiquitin-dependent protein catabolic process GO:0016567 - protein ubiquitination GO:0032436 - positive regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process and 2 others more... |
| Homologous interactions | 19 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
