Protein: CDC4
Cell division control protein 4 (E3 ubiquitin ligase complex SCF subunit CDC4) (F-box protein CDC4)

Gene: CDC4
Organism: Saccharomyces cerevisiae S288C
Interactions: 59
UniProt ID: P07834

Gene Ontology (top 5):
GO:0000082 - G1/S transition of mitotic cell cycle
GO:0000086 - G2/M transition of mitotic cell cycle
GO:0000472 - endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000480 - endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

460737

SKP1
Suppressor of kinetochore protein 1

28

20

Small-scale

0.993

High

460748

CDC53
Cell division control protein 53

15

20

Small-scale

0.985

High

460708

UBC3
Ubiquitin-conjugating enzyme E2-34 kDa

12

17

Small-scale

0.979

High

460697

CDC4
Cell division control protein 4

4

18

Small-scale

0.899

High

460722

CENPA
Histone H3-like centromeric protein CSE4

2

13

Small-scale

0.754

High

460746

RBX1
RING-box protein HRT1

8

11

Small-scale

0.750

High

460700

CDC6
Cell division control protein 6

8

3

Small-scale

0.743

High

460724

SIC1
Protein SIC1

24

0

Small-scale

0.736

High

460702

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

12

Small-scale

0.710

High

460738

HST3
NAD-dependent histone deacetylase HST3

3

9

Small-scale

0.646

High

460707

CG13
G1/S-specific cyclin CLN3

3

7

Small-scale

0.640

High

460719

ASH1
Transcriptional regulatory protein ASH1

3

0

Small-scale

0.632

High

460712

FAR1
Cyclin-dependent kinase inhibitor FAR1

3

0

Small-scale

0.623

High

460728

MET30
F-box protein MET30

1

19

Small-scale

0.618

High

460736

MAD3
Spindle assembly checkpoint component MAD3

1

1

Small-scale

0.618

High

460739

HST4
NAD-dependent histone deacetylase HST4

2

9

Small-scale

0.611

High

460698

SWI5
Transcriptional factor SWI5

2

10

Small-scale

0.600

High

460725

CIC1
Proteasome-interacting protein CIC1

1

5

Small-scale

0.586

High

460711

CG12
G1/S-specific cyclin CLN2

2

11

Small-scale

0.584

High

395212

GCN4
General control transcription factor GCN4

2

0

Small-scale

0.579

High

460699

GPA1
Guanine nucleotide-binding protein alpha-1 subunit

1

3

Small-scale

0.579

High

460709

TEC1
Ty transcription activator TEC1

2

0

Small-scale

0.577

High

460723

RCN1
Calcipressin-like protein

2

0

Small-scale

0.570

High

460731

PSA4
Proteasome subunit alpha type-4

1

7

Small-scale

0.536

High

460729

TCPG
T-complex protein 1 subunit gamma

1

20

High-throughput

0.514

High

448845

STE7
Serine/threonine-protein kinase STE7

1

20

Small-scale

0.512

High

460747

SGT1
Protein SGT1

1

2

Small-scale

0.512

High

460740

FPK1
Flippase kinase 1

1

12

Small-scale

0.501

High

460742

YD132
Uncharacterized protein YDR132C

1

0

High-throughput

0.486

High

460720

SLD2
DNA replication regulator SLD2

1

0

Small-scale

0.480

High

460744

PLM2
Protein PLM2

1

0

Small-scale

0.480

High

460750

WHI5
G1-specific transcriptional repressor WHI5

1

0

Small-scale

0.480

High

401823

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

5

High-throughput

0.479

High

460710

CG11
G1/S-specific cyclin CLN1

1

17

Small-scale

0.479

High

460714

CG23
G2/mitotic-specific cyclin-3

1

4

Small-scale

0.479

High

460717

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.479

High

460741

PRS8
26S proteasome regulatory subunit 8 homolog

1

8

Small-scale

0.479

High

460732

HAC1
Transcriptional activator HAC1

1

0

Small-scale

0.460

High

460701

SWI1
SWI/SNF chromatin-remodeling complex subunit SWI1

1

0

Small-scale

0.458

High

460713

PCL1
PHO85 cyclin-1

1

0

Small-scale

0.458

High

460718

STE5
Protein STE5

1

0

Small-scale

0.458

High

460743

LIC4
Protein ATC1/LIC4

1

0

Small-scale

0.458

High

460706

KIN2
Serine/threonine-protein kinase KIN2

1

5

Small-scale

0.457

High

460703

HSP71
Heat shock protein SSA1

1

12

High-throughput

0.445

High

460704

HSP72
Heat shock protein SSA2

1

14

High-throughput

0.445

High

460705

SSB1
Ribosome-associated molecular chaperone SSB1

1

16

High-throughput

0.445

High

460715

SIS1
Protein SIS1

1

9

High-throughput

0.445

High

460716

MAS5
Mitochondrial protein import protein MAS5

1

9

High-throughput

0.445

High

460726

SSZ1
Ribosome-associated complex subunit SSZ1

1

12

High-throughput

0.445

High

460730

SSB2
Ribosome-associated molecular chaperone SSB2

1

16

High-throughput

0.445

High

460749

CWC2
Pre-mRNA-splicing factor CWC2

1

1

High-throughput

0.417

High

460733

ECO1
N-acetyltransferase ECO1

1

0

Small-scale

0.391

High

460751

LAG2
Cullin-associated NEDD8-dissociated protein 1 homolog

1

0

Small-scale

0.301

High

460734

SPO74
Sporulation-specific protein 74

1

0

Small-scale

0.265

Low

460721

YKF0
Uncharacterized protein YKL050C

1

0

Small-scale

0.261

Low

460727

CYC2
Cytochrome c mitochondrial import factor CYC2

1

0

Small-scale

0.261

Low

460745

ISR1
Serine/threonine-protein kinase ISR1

1

0

Small-scale

0.249

Low

460735

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025