HitPredict

Interactor 1: DOCK7 (Q96N67)
Dedicator of cytokinesis protein 7
Gene: DOCK7

Interactor 2: LRCH1 (Q9Y2L9)
Leucine-rich repeat and calponin homology domain-containing protein 1 (Calponin homology domain-containing protein 1) (Neuronal protein 81) (NP81)
Gene: LRCH1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.90	0.50	0.672

Property	Details
Experiments	29467281, 32203420, 33961781, 35271311, 24255178, unassigned2213
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 2140 Hs			1 728
+	Hs
		1244090 DOCK8_HUMAN (2-2139): 0: 2478: 55.69		LRCH1_HUMAN (1-728): 3.4e-151: 459: 100.00
+	Hs
		264517 DOCK7_HUMAN (1-2140): 0: 2782: 100.00		LRCH4_HUMAN (5-187): 2.31e-23: 107: 17.35
+	Hs
		1294469 DOCK7_HUMAN (1-2140): 0: 2782: 100.00		LRCH3_HUMAN (5-163): 5.58e-20: 97.1: 17.54
+	Hs
		1293670 DOCK6_HUMAN (2-2140): 0: 2420: 64.50		LRCH1_HUMAN (1-728): 3.4e-151: 459: 100.00
+	Hs
		1138582 DOCK7_HUMAN (1-2140): 0: 2782: 100.00		LRCH2_HUMAN (6-170): 2e-19: 95.2: 14.69
+	Hs
		264512 DOCK8_HUMAN (2-2139): 0: 2478: 55.69		LRCH4_HUMAN (5-187): 2.31e-23: 107: 17.35
+	Hs
		1244072 DOCK8_HUMAN (2-2139): 0: 2478: 55.69		LRCH3_HUMAN (5-163): 5.58e-20: 97.1: 17.54
+	Hs
		1138572 DOCK8_HUMAN (2-2139): 0: 2478: 55.69		LRCH2_HUMAN (6-170): 2e-19: 95.2: 14.69
+	Hs
		264515 DOCK6_HUMAN (2-2140): 0: 2420: 64.50		LRCH4_HUMAN (5-187): 2.31e-23: 107: 17.35
+	Hs
		1293663 DOCK6_HUMAN (2-2140): 0: 2420: 64.50		LRCH3_HUMAN (5-163): 5.58e-20: 97.1: 17.54
+	Hs
		1138578 DOCK6_HUMAN (2-2140): 0: 2420: 64.50		LRCH2_HUMAN (6-170): 2e-19: 95.2: 14.69
+	Hs
		1138589 DOCK5_HUMAN (303-859): 3.61e-76: 284: 15.15		LRCH2_HUMAN (6-170): 2e-19: 95.2: 14.69