Interactor 1: VRK1 (Q99986)
Serine/threonine-protein kinase VRK1 (EC 2.7.11.1) (Vaccinia-related kinase 1)
Gene: VRK1

Interactor 2: PLK3 (Q9H4B4)
Serine/threonine-protein kinase PLK3 (EC 2.7.11.21) (Cytokine-inducible serine/threonine-protein kinase) (FGF-inducible kinase) (Polo-like kinase 3) (PLK-3) (Proliferation-related kinase)
Gene: PLK3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.55 1.00 0.747

The method score is based on:

Property Details
Experiments 19103756
Identification Methods anti tag coimmunoprecipitation, pull down, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase
Common GO terms GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
and 5 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 396
Hs

1 646
+ Hs
+ Hs
+ Ce
+ Sc
+ At
+ Hs
+ At
+ Hs
+ At
+ Zm
+ At
+ Rn
+ At
+ At
+ At
+ At

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Last updated: 15 Jul 2024