HitPredict

Interactor 1: RIMS1 (Q99NE5)
Regulating synaptic membrane exocytosis protein 1 (Rab-3-interacting molecule 1) (RIM 1) (Rab-3-interacting protein 1)
Gene: RIMS1

Interactor 2: RAB3B (Q9CZT8)
Ras-related protein Rab-3B
Gene: RAB3B

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	12578829
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	FYVE_2~Ras, PDZ~Ras
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1463 Mm			1 219
+	Mm
		722691 RIMS1_MOUSE (1-1463): 0: 923: 100.00		RAB3D_MOUSE (1-219): 1.46e-89: 264: 76.71
+	Mm
		919021 RIMS1_MOUSE (1-1463): 0: 923: 100.00		RAB3C_MOUSE (1-219): 8.73e-86: 255: 79.91
+	Mm
		926089 RIMS1_MOUSE (1-1463): 0: 923: 100.00		RAB3A_MOUSE (1-219): 1.09e-85: 254: 77.73
+	Mm
		895586 RIMS1_MOUSE (1-1463): 0: 923: 100.00		RAB10_MOUSE (15-186): 5.19e-63: 196: 52.91
+	Mm
		722693 RIMS2_MOUSE (1-1463): 3.21e-149: 496: 33.33		RAB3D_MOUSE (1-219): 1.46e-89: 264: 76.71
+	Mm
		1321910 RIMS2_MOUSE (1-1463): 3.21e-149: 496: 33.33		RAB3B_MOUSE (1-219): 1.61e-86: 256: 100.00
+	Mm
		919024 RIMS2_MOUSE (1-1463): 3.21e-149: 496: 33.33		RAB3C_MOUSE (1-219): 8.73e-86: 255: 79.91
+	Mm
		926097 RIMS2_MOUSE (1-1463): 3.21e-149: 496: 33.33		RAB3A_MOUSE (1-219): 1.09e-85: 254: 77.73
+	Mm
		877203 RIMS2_MOUSE (1-1463): 3.21e-149: 496: 33.33		RAB8A_MOUSE (17-207): 1.24e-61: 192: 49.22
+	Hs
		896680 WWP1_HUMAN (570-1177): 3.32e-57: 217: 12.94		RAB14_HUMAN (14-219): 2.86e-99: 288: 35.68
+	Hs
		896633 SYT6_HUMAN (1040-1439): 8.01e-46: 175: 16.32		RAB14_HUMAN (14-219): 2.86e-99: 288: 35.68
+	Rn
		222478 RPH3L_RAT (50-338): 4.82e-55: 196: 16.55		RAB3A_RAT (1-219): 1.09e-85: 254: 77.73
+	Hs
		1134943 SYT6_HUMAN (1040-1439): 8.01e-46: 175: 16.32		RAB1B_HUMAN (15-219): 7.91e-89: 261: 41.95
+	Ce
		1094851 RIM_CAEEL (73-380): 3e-41: 168: 17.69		RAB3_CAEEL (1-219): 1.13e-88: 262: 70.78
+	Mm
		722679 RP3A_MOUSE (908-1443): 2.41e-38: 156: 12.09		RAB3D_MOUSE (1-219): 1.46e-89: 264: 76.71
+	Mm
		812777 RP3A_MOUSE (908-1443): 2.41e-38: 156: 12.09		RAB3B_MOUSE (1-219): 1.61e-86: 256: 100.00
+	Mm
		812771 RP3A_MOUSE (908-1443): 2.41e-38: 156: 12.09		RAB3C_MOUSE (1-219): 8.73e-86: 255: 79.91
+	Mm
		812772 RP3A_MOUSE (908-1443): 2.41e-38: 156: 12.09		RAB3A_MOUSE (1-219): 1.09e-85: 254: 77.73
+	Rn
		812780 RP3A_RAT (791-1443): 1.91e-37: 153: 9.94		RAB3A_RAT (1-219): 1.09e-85: 254: 77.73
+	Mm
		812770 RP3A_MOUSE (908-1443): 2.41e-38: 156: 12.09		RAB8A_MOUSE (17-207): 1.24e-61: 192: 49.22