HitPredict

Interactor 1: PSDE (O00487)
26S proteasome non-ATPase regulatory subunit 14 (EC 3.4.19.-) (26S proteasome regulatory subunit RPN11) (26S proteasome-associated PAD1 homolog 1)
Gene: PSMD14

Interactor 2: IKKE (Q14164)
Inhibitor of nuclear factor kappa-B kinase subunit epsilon (I-kappa-B kinase epsilon) (IKK-E) (IKK-epsilon) (IkBKE) (EC 2.7.11.10) (Inducible I kappa-B kinase) (IKK-i)
Gene: IKBKE

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	32476569, 17353931
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 310 Hs			1 716
+	Hs
		130883 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		KCC1A_HUMAN (3-389): 7.57e-121: 367: 20.16
+	Hs
		158519 CSN5_HUMAN (1-305): 6.24e-83: 255: 28.35		IKKB_HUMAN (9-701): 6.33e-128: 399: 18.97
+	Hs
		849196 PSMD7_HUMAN (28-185): 3.22e-34: 128: 22.56		IKKE_HUMAN (1-716): 1.32e-170: 508: 100.00
+	Hs
		167593 CSN5_HUMAN (1-305): 6.24e-83: 255: 28.35		IKKA_HUMAN (9-700): 5.05e-116: 367: 18.31
+	Hs
		850690 CSN5_HUMAN (1-305): 6.24e-83: 255: 28.35		KS6A3_HUMAN (6-294): 2.42e-88: 294: 22.34
+	Hs
		130981 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		ULK2_HUMAN (1-221): 7.38e-24: 109: 31.28
+	Hs
		262212 STABP_HUMAN (17-199): 5.28e-44: 157: 17.84		ULK1_HUMAN (2-221): 1.05e-23: 109: 31.72
+	Hs
		262302 STALP_HUMAN (18-208): 4.08e-42: 152: 18.65		ULK1_HUMAN (2-221): 1.05e-23: 109: 31.72