HitPredict

Interactor 1: NUD12 (Q9BQG2)
NAD-capped RNA hydrolase NUDT12 (DeNADding enzyme NUDT12) (EC 3.6.1.-) (NADH pyrophosphatase NUDT12) (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12)
Gene: NUDT12

Interactor 2: ZO2 (Q9UDY2)
Tight junction protein ZO-2 (Tight junction protein 2) (Zona occludens protein 2) (Zonula occludens protein 2)
Gene: TJP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 462 Hs			1 1190
+	Hs
		1354501 ANR50_HUMAN (2-174): 2.97e-30: 126: 19.65		ZO2_HUMAN (1-1190): 0: 838: 100.00
+	Hs
		990881 MIB1_HUMAN (203-441): 4e-10: 64.4: 9.76		ZO1_HUMAN (19-1187): 5.94e-133: 447: 36.80
+	Mm
		103602 ANK3_MOUSE (140-454): 1.89e-24: 109: 9.27		DLG4_MOUSE (3-423): 3.16e-52: 198: 18.89
+	Mm
		1143421 ANK2_MOUSE (162-454): 2.46e-24: 109: 9.44		DLG4_MOUSE (3-423): 3.16e-52: 198: 18.89
+	Mm
		1143380 DAPK1_MOUSE (5-251): 2.69e-19: 93.3: 14.86		DLG4_MOUSE (3-423): 3.16e-52: 198: 18.89
+	Mm
		1012698 TANC1_MOUSE (2-227): 3.24e-13: 74.4: 12.04		DLG4_MOUSE (3-423): 3.16e-52: 198: 18.89
+	Hs
		942379 TANC1_HUMAN (2-235): 1.5e-12: 72.1: 14.09		DLG4_HUMAN (3-423): 2.31e-52: 199: 18.89
+	Rn
		677797 TANC1_RAT (2-235): 2.8e-12: 71.3: 13.06		DLG4_RAT (3-423): 1.74e-52: 199: 18.89
+	Hs
		1021559 TANC1_HUMAN (2-235): 1.5e-12: 72.1: 14.09		DLG1_HUMAN (1-515): 2.7e-47: 185: 16.38
+	Rn
		1144016 TANC1_RAT (2-235): 2.8e-12: 71.3: 13.06		DLG1_RAT (1-513): 8.04e-44: 174: 16.64
+	Dm
		677732 Q9W2I0_DROME (5-279): 9.71e-12: 69.4: 19.80		DLG1_DROME (12-421): 3.86e-35: 147: 17.36
+	Hs
		1021434 ANK3_HUMAN (280-459): 6.6e-16: 82.9: 12.90		DLG5_HUMAN (25-522): 2.43e-14: 80.4: 11.77