HitPredict

Interactor 1: LZTS2 (Q9BRK4)
Leucine zipper putative tumor suppressor 2 (hLZTS2) (Protein LAPSER1)
Gene: LZTS2

Interactor 2: SI1L2 (Q9P2F8)
Signal-induced proliferation-associated 1-like protein 2 (SIPA1-like protein 2)
Gene: SIPA1L2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.50	0.633

Property	Details
Experiments	26186194, 28514442, 29395067, 33961781
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 669 Hs			1 1722
+	Hs
		1350316 LZTS1_HUMAN (26-653): 2.54e-34: 140: 35.06		SI1L2_HUMAN (1-1722): 0: 1821: 100.00
+	Hs
		165788 N4BP3_HUMAN (17-640): 5.23e-34: 139: 27.16		SI1L2_HUMAN (1-1722): 0: 1821: 100.00
+	Hs
		230555 LZTS3_HUMAN (1-669): 7.26e-32: 133: 31.62		SI1L2_HUMAN (1-1722): 0: 1821: 100.00
+	Hs
		1145965 CP135_HUMAN (300-610): 1.6e-09: 63.5: 21.52		SI1L2_HUMAN (1-1722): 0: 1821: 100.00
+	Hs
		196501 LZTS2_HUMAN (1-669): 6.28e-56: 203: 100.00		SI1L1_HUMAN (1-1719): 0: 1424: 48.02
+	Hs
		196381 LZTS3_HUMAN (1-669): 7.26e-32: 133: 31.62		SI1L1_HUMAN (1-1719): 0: 1424: 48.02
+	Hs
		230273 LZTS2_HUMAN (1-669): 6.28e-56: 203: 100.00		SI1L3_HUMAN (19-1714): 0: 1313: 42.85
+	Hs
		196455 CP135_HUMAN (300-610): 1.6e-09: 63.5: 21.52		SI1L1_HUMAN (1-1719): 0: 1424: 48.02
+	Hs
		230186 LZTS3_HUMAN (1-669): 7.26e-32: 133: 31.62		SI1L3_HUMAN (19-1714): 0: 1313: 42.85
+	Hs
		230265 MY18A_HUMAN (329-637): 1.72e-11: 70: 17.67		SI1L3_HUMAN (19-1714): 0: 1313: 42.85
+	Hs
		230253 CP135_HUMAN (300-610): 1.6e-09: 63.5: 21.52		SI1L3_HUMAN (19-1714): 0: 1313: 42.85
+	Mm
		1142070 TSC1_MOUSE (48-630): 3.36e-32: 135: 13.67		TSC2_MOUSE (538-860): 4.04e-102: 365: 19.65
+	Rn
		835139 TSC1_RAT (48-630): 5.02e-27: 119: 13.44		TSC2_RAT (538-860): 7.73e-102: 365: 19.10
+	Hs
		148885 CTRO_HUMAN (327-578): 7.02e-09: 61.3: 16.36		RGPA2_HUMAN (502-852): 1.14e-101: 364: 21.63
+	Hs
		1061846 SLMAP_HUMAN (328-641): 1.08e-09: 63.9: 19.94		RGPA1_HUMAN (504-833): 7.23e-95: 343: 22.99
+	Mm
		1112023 TSC1_MOUSE (48-630): 3.36e-32: 135: 13.67		Q3TQ10_MOUSE (639-860): 2.1e-78: 261: 18.57
+	Hs
		1291406 LZTS2_HUMAN (1-669): 6.28e-56: 203: 100.00		SIPA1_HUMAN (1389-1707): 1.51e-20: 101: 18.71
+	Hs
		1068686 PLEC_HUMAN (327-659): 1.61e-09: 63.5: 20.77		RHG23_HUMAN (960-1528): 4.6e-39: 162: 13.57
+	Hs
		149481 CTRO_HUMAN (327-578): 7.02e-09: 61.3: 16.36		PCLO_HUMAN (1043-1712): 2.32e-13: 78.1: 8.16