Protein: SFPA2
Pulmonary surfactant-associated protein A2 (PSP-A) (PSPA) (SP-A) (SP-A2) (35 kDa pulmonary surfactant-associated protein) (Alveolar proteinosis protein) (Collectin-5)

Gene: SFPA2, SFTPA2
Organism: Homo sapiens
Interactions: 47
UniProt ID: Q8IWL1

Gene Ontology (top 5):
GO:0005576 - extracellular region
GO:0005581 - collagen trimer
GO:0005615 - extracellular space
GO:0005771 - multivesicular body
GO:0005789 - endoplasmic reticulum membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

62978

POTEF
POTE ankyrin domain family member F

1

4

High-throughput

0.691

High

1052161

COEA1
Collagen alpha-1(XIV) chain

1

19

High-throughput

0.691

High

551803

CO6A1

1

19

High-throughput

0.575

High

551876

CO6A2

1

19

High-throughput

0.575

High

1310197

COCA1

1

20

High-throughput

0.575

High

1310199

UBQL2
Ubiquilin-2

2

2

High-throughput

0.553

High

126322

TLR4
Toll-like receptor 4

1

12

Small-scale

0.553

High

171505

S27A2
Long-chain fatty acid transport protein 2

1

1

High-throughput

0.536

High

327113

NXPH4
Neurexophilin-4

1

1

High-throughput

0.536

High

810619

COIA1
Collagen alpha-1(XVIII) chain [Cleaved into: Endostatin; Non-collagenous domain 1

1

19

High-throughput

0.536

High

922461

CLH2
Clathrin heavy chain 2

1

1

High-throughput

0.536

High

1194500

ERFE
Erythroferrone

1

1

High-throughput

0.536

High

528767

MGST1
Microsomal glutathione S-transferase 1

1

0

High-throughput

0.513

High

170514

RAB7L
Ras-related protein Rab-7L1

1

13

High-throughput

0.489

High

240100

KPRB
Phosphoribosyl pyrophosphate synthase-associated protein 2

1

1

High-throughput

0.489

High

292165

S2512
Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial

1

5

High-throughput

0.489

High

822745

VHL
von Hippel-Lindau disease tumor suppressor

1

3

High-throughput

0.489

High

922320

LIMK2
LIM domain kinase 2

1

4

High-throughput

0.489

High

1181393

P3H1
Prolyl 3-hydroxylase 1

1

13

High-throughput

0.489

High

1208452

EOGT
EGF domain-specific O-linked N-acetylglucosamine transferase

1

1

High-throughput

0.489

High

1228351

GL8D1
Glycosyltransferase 8 domain-containing protein 1

1

1

High-throughput

0.489

High

1308837

P3H3
Prolyl 3-hydroxylase 3

1

13

High-throughput

0.489

High

1310194

AURKB
Aurora kinase B

1

1

High-throughput

0.489

High

1310195

SFXN2
Sideroflexin-2

1

1

High-throughput

0.489

High

1310196

CK5P1
Mitochondrial tRNA methylthiotransferase CDK5RAP1

1

1

High-throughput

0.489

High

1310198

MTG2
Mitochondrial ribosome-associated GTPase 2

1

6

High-throughput

0.489

High

1310200

S2513
Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial

1

5

High-throughput

0.489

High

1310201

DD19B
ATP-dependent RNA helicase DDX19B

1

4

High-throughput

0.489

High

1310202

XCT
Cystine/glutamate transporter

1

4

High-throughput

0.489

High

1310203

ORNT1
Mitochondrial ornithine transporter 1

1

7

High-throughput

0.489

High

730750

1433S
14-3-3 protein sigma

1

8

Small-scale

0.479

High

1310204

LY96
Lymphocyte antigen 96

1

3

Small-scale

0.479

High

404199

GCR
Glucocorticoid receptor

1

2

High-throughput

0.437

High

691220

1433T
14-3-3 protein theta

1

8

Small-scale

0.437

High

730036

1433B
14-3-3 protein beta/alpha

1

8

Small-scale

0.437

High

966583

1433G
14-3-3 protein gamma

1

8

Small-scale

0.437

High

971752

1433E
14-3-3 protein epsilon

1

1

Small-scale

0.437

High

1049529

1433F
14-3-3 protein eta

1

8

Small-scale

0.437

High

954530

PRPS1
Ribose-phosphate pyrophosphokinase 1

1

1

High-throughput

0.407

High

1310193

SC65
Endoplasmic reticulum protein SC65

1

13

High-throughput

0.407

High

968643

NCS1
Neuronal calcium sensor 1

2

0

High-throughput

0.316

High

890206

HINT1
Adenosine 5'-monophosphoramidase HINT1

1

0

High-throughput

0.279

Low

1025820

BORG5
Cdc42 effector protein 1

1

0

High-throughput

0.279

Low

1211775

SYRM
Probable arginine--tRNA ligase, mitochondrial

1

0

High-throughput

0.279

Low

1310191

RPTOR
Regulatory-associated protein of mTOR

1

0

High-throughput

0.279

Low

1310192

PTCD2
Pentatricopeptide repeat-containing protein 2, mitochondrial

1

0

High-throughput

0.279

Low

87501

OSCRI
SCRIB overlapping open reading frame protein

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025