HitPredict

Interactor 1: ESYT1 (Q9BSJ8)
Extended synaptotagmin-1 (E-Syt1) (Membrane-bound C2 domain-containing protein)
Gene: ESYT1

Interactor 2: DHRS7 (Q9Y394)
Dehydrogenase/reductase SDR family member 7 (EC 1.1.1.-) (Retinal short-chain dehydrogenase/reductase 4) (retSDR4) (Short chain dehydrogenase/reductase family 34C member 1) (Protein SDR34C1)
Gene: DHRS7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	35271311, 37931956
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005789 - endoplasmic reticulum membrane GO:0016020 - membrane
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1104 Hs			1 339
+	Hs
		1253239 ESYT1_HUMAN (1-1104): 0: 874: 100.00		RDH11_HUMAN (42-300): 2.53e-68: 218: 25.09
+	Hs
		1240279 ESYT1_HUMAN (1-1104): 0: 874: 100.00		DHB11_HUMAN (43-311): 2.07e-68: 217: 27.31
+	Hs
		48561 ESYT2_HUMAN (848-1101): 9e-14: 78.1: 12.32		DHRS7_HUMAN (1-339): 3.04e-101: 303: 100.00
+	Hs
		48388 ESYT2_HUMAN (848-1101): 9e-14: 78.1: 12.32		DRS7B_HUMAN (20-322): 1.55e-73: 232: 32.46
+	Dm
		52047 Q7K3H0_DROME (922-1095): 2.72e-14: 80.1: 33.52		A1Z729_DROME (12-311): 2.43e-67: 216: 19.75
+	Hs
		48423 ESYT2_HUMAN (848-1101): 9e-14: 78.1: 12.32		DHB11_HUMAN (43-311): 2.07e-68: 217: 27.31