HitPredict

Interactor 1: SSBP3 (Q9BWW4)
Single-stranded DNA-binding protein 3 (Sequence-specific single-stranded-DNA-binding protein)
Gene: SSBP3

Interactor 2: LHX3 (Q9UBR4)
LIM/homeobox protein Lhx3 (LIM homeobox protein 3)
Gene: LHX3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	33961781, 35140242
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005667 - transcription regulator complex GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 388 Hs			1 397
+	Mm
		292011 SSBP3_MOUSE (1-388): 5.14e-67: 218: 100.00		LMX1B_MOUSE (1-339): 4.48e-65: 214: 28.50
+	Hs
		238119 SSBP3_HUMAN (1-388): 5.14e-67: 218: 100.00		LMX1B_HUMAN (1-339): 4.26e-64: 212: 28.54
+	Hs
		822674 SSBP3_HUMAN (1-388): 5.14e-67: 218: 100.00		LHX1_HUMAN (31-396): 6.18e-62: 206: 32.21
+	Hs
		238118 SSBP4_HUMAN (5-388): 9.47e-57: 192: 69.25		LMX1B_HUMAN (1-339): 4.26e-64: 212: 28.54
+	Hs
		1314903 SSBP3_HUMAN (1-388): 5.14e-67: 218: 100.00		LHX9_HUMAN (4-154): 9.27e-51: 176: 41.56
+	Mm
		1321926 SSBP3_MOUSE (1-388): 5.14e-67: 218: 100.00		LHX9_MOUSE (4-154): 8.24e-50: 174: 41.56
+	Hs
		899933 SSBP3_HUMAN (1-388): 5.14e-67: 218: 100.00		ISL1_HUMAN (21-309): 5.65e-50: 173: 27.60
+	Mm
		899944 SSBP3_MOUSE (1-388): 5.14e-67: 218: 100.00		ISL1_MOUSE (21-309): 5.65e-50: 173: 27.60
+	Hs
		1148491 SSBP3_HUMAN (1-388): 5.14e-67: 218: 100.00		LHX8_HUMAN (30-290): 3.86e-49: 171: 29.12
+	Hs
		1251454 SSBP3_HUMAN (1-388): 5.14e-67: 218: 100.00		LMO3_HUMAN (31-159): 1.12e-51: 171: 41.05
+	Hs
		638571 SSBP3_HUMAN (1-388): 5.14e-67: 218: 100.00		RBTN1_HUMAN (31-149): 1.03e-50: 169: 42.74
+	Hs
		1283496 SSBP3_HUMAN (1-388): 5.14e-67: 218: 100.00		ISL2_HUMAN (21-321): 3.61e-46: 164: 27.75
+	Hs
		1314911 SSBP3_HUMAN (1-388): 5.14e-67: 218: 100.00		LHX6_HUMAN (14-253): 5.91e-46: 163: 31.18
+	Mm
		1321868 SSBP3_MOUSE (1-388): 5.14e-67: 218: 100.00		ISL2_MOUSE (21-321): 9.38e-46: 162: 27.75
+	Hs
		638570 SSBP4_HUMAN (5-388): 9.47e-57: 192: 69.25		RBTN1_HUMAN (31-149): 1.03e-50: 169: 42.74
+	Hs
		903773 SSBP3_HUMAN (1-388): 5.14e-67: 218: 100.00		LMO4_HUMAN (31-148): 2.3e-28: 110: 43.09
+	Mm
		1321929 SSBP3_MOUSE (1-388): 5.14e-67: 218: 100.00		LHX2_MOUSE (136-281): 4.23e-15: 78.3: 23.90
+	Hs
		839819 SSBP3_HUMAN (1-388): 5.14e-67: 218: 100.00		LHX2_HUMAN (136-281): 4.68e-15: 77.9: 23.90
+	Hs
		110821 SSBP3_HUMAN (1-388): 5.14e-67: 218: 100.00		H7C0H1_HUMAN (136-281): 8.57e-15: 77.2: 23.90
+	Hs
		1281179 SSBP3_HUMAN (1-388): 5.14e-67: 218: 100.00		LHX4_HUMAN (8-83): 1.09e-13: 73.9: 25.00