Protein: CCNL2
Cyclin-L2 (Paneth cell-enhanced expression protein)

Gene: CCNL2
Organism: Homo sapiens
Interactions: 92
UniProt ID: Q96S94

Gene Ontology (top 5):
GO:0000307 - cyclin-dependent protein kinase holoenzyme complex
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0016538 - cyclin-dependent protein serine/threonine kinase regulator activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1301925

CD11A
Cyclin-dependent kinase 11A

4

20

Small-scale

0.895

High

934411

CSK21
Casein kinase II subunit alpha

3

20

Small-scale

0.861

High

1242191

CCNY
Cyclin-Y

3

0

High-throughput

0.816

High

586932

CSK22
Casein kinase II subunit alpha'

2

20

High-throughput

0.811

High

609689

KAPCG
cAMP-dependent protein kinase catalytic subunit gamma

1

3

High-throughput

0.691

High

523120

SRC
Proto-oncogene tyrosine-protein kinase Src

3

4

High-throughput

0.667

High

719591

MERL
Merlin

3

3

High-throughput

0.667

High

1040507

SNX1
Sorting nexin-1

3

2

High-throughput

0.667

High

1157364

JMJD6
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6

3

2

Small-scale

0.667

High

1191138

I2BP2
Interferon regulatory factor 2-binding protein 2

3

1

High-throughput

0.667

High

1215908

I2BP1
Interferon regulatory factor 2-binding protein 1

3

1

High-throughput

0.667

High

1044080

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

20

Small-scale

0.647

High

1123881

RUN3A
RUN domain-containing protein 3A

3

0

High-throughput

0.646

High

200302

ZBT43
Zinc finger and BTB domain-containing protein 43

2

2

High-throughput

0.628

High

566461

KPCA
Protein kinase C alpha type

1

3

High-throughput

0.618

High

610769

KAPCB
cAMP-dependent protein kinase catalytic subunit beta

1

3

High-throughput

0.618

High

841297

CDK7
Cyclin-dependent kinase 7

1

20

High-throughput

0.618

High

412319

FYN
Tyrosine-protein kinase Fyn

2

4

High-throughput

0.611

High

1022308

CSTF3
Cleavage stimulation factor subunit 3

2

1

High-throughput

0.611

High

1070603

RNPS1
RNA-binding protein with serine-rich domain 1

2

4

High-throughput

0.611

High

816827

IREB2
Iron-responsive element-binding protein 2

3

3

High-throughput

0.609

High

1301915

ULBP3
UL16-binding protein 3

3

1

High-throughput

0.609

High

169729

ZBT7B
Zinc finger and BTB domain-containing protein 7B

2

1

High-throughput

0.606

High

180422

MAGB2
Melanoma-associated antigen B2

2

1

High-throughput

0.606

High

1301913

MDFI
MyoD family inhibitor

2

1

High-throughput

0.606

High

839069

EMD
Emerin

2

0

High-throughput

0.580

High

433457

YES
Tyrosine-protein kinase Yes

2

4

High-throughput

0.558

High

488090

RRAS
Ras-related protein R-Ras

2

1

High-throughput

0.558

High

580448

GNAZ
Guanine nucleotide-binding protein G(z) subunit alpha

2

2

High-throughput

0.558

High

837644

GNAQ
Guanine nucleotide-binding protein G(q) subunit alpha

2

2

High-throughput

0.558

High

887413

KR122
Keratin-associated protein 12-2

2

2

High-throughput

0.553

High

1205610

F90A1
Protein FAM90A1

2

1

High-throughput

0.553

High

1261078

TRI41
E3 ubiquitin-protein ligase TRIM41

2

3

High-throughput

0.553

High

1301926

UBP20
Ubiquitin carboxyl-terminal hydrolase 20

2

2

High-throughput

0.553

High

1301928

DCAF1
DDB1- and CUL4-associated factor 1

1

5

Small-scale

0.552

High

181556

CLOCK
Circadian locomoter output cycles protein kaput

1

2

High-throughput

0.536

High

751784

GRP75
Stress-70 protein, mitochondrial

1

1

High-throughput

0.536

High

796162

MAGA9
Melanoma-associated antigen 9

1

1

High-throughput

0.536

High

854203

JAK3
Tyrosine-protein kinase JAK3

1

5

High-throughput

0.536

High

1038648

HDAC1
Histone deacetylase 1

1

1

High-throughput

0.536

High

1059556

KIF22
Kinesin-like protein KIF22

1

1

High-throughput

0.536

High

1163320

FIGLA
Factor in the germline alpha

1

1

High-throughput

0.536

High

1252768

ZCRB1
Zinc finger CCHC-type and RNA-binding motif-containing protein 1

1

9

High-throughput

0.536

High

1301922

S30BP
SAP30-binding protein

1

1

High-throughput

0.536

High

276093

CBR3
Carbonyl reductase [NADPH] 3

1

0

High-throughput

0.513

High

887600

APC15
Anaphase-promoting complex subunit 15

1

0

High-throughput

0.513

High

1184462

CENPQ
Centromere protein Q

1

0

High-throughput

0.513

High

1205801

P66A
Transcriptional repressor p66-alpha

1

0

High-throughput

0.513

High

1301914

MND1
Meiotic nuclear division protein 1 homolog

1

0

High-throughput

0.513

High

1166535

BTNL9
Butyrophilin-like protein 9

1

4

High-throughput

0.489

High

1201400

LRRT4
Leucine-rich repeat transmembrane neuronal protein 4

1

1

High-throughput

0.489

High

1220264

DHX40
Probable ATP-dependent RNA helicase DHX40

1

1

High-throughput

0.489

High

1271793

KIFA3
Kinesin-associated protein 3

1

5

High-throughput

0.489

High

299452

UBXN7
UBX domain-containing protein 7

1

1

High-throughput

0.479

High

304302

UBR5
E3 ubiquitin-protein ligase UBR5

1

8

High-throughput

0.479

High

433958

LYN
Tyrosine-protein kinase Lyn

1

4

High-throughput

0.479

High

506647

BCR
Breakpoint cluster region protein

1

3

High-throughput

0.479

High

625007

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

5

Small-scale

0.479

High

652024

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

7

High-throughput

0.479

High

931809

CSK2B
Casein kinase II subunit beta

1

3

High-throughput

0.479

High

1067106

BRD3
Bromodomain-containing protein 3

1

14

High-throughput

0.479

High

1301921

ZRAN1
Ubiquitin thioesterase ZRANB1

1

8

High-throughput

0.479

High

1301923

SNX6
Sorting nexin-6

1

2

High-throughput

0.479

High

1301927

SAMH1
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1

1

1

Small-scale

0.479

High

827537

EFTU
Elongation factor Tu, mitochondrial

1

2

High-throughput

0.470

High

237618

DIAP1
Protein diaphanous homolog 1

1

0

High-throughput

0.458

High

1014068

AP1B1
AP-1 complex subunit beta-1

1

0

High-throughput

0.458

High

1161824

FBX38
F-box only protein 38

1

0

High-throughput

0.458

High

1301916

EHD1
EH domain-containing protein 1

1

0

High-throughput

0.458

High

952090

SRSF3
Serine/arginine-rich splicing factor 3

1

16

Small-scale

0.445

High

964048

SRSF2
Serine/arginine-rich splicing factor 2

1

8

Small-scale

0.445

High

992895

SRSF1
Serine/arginine-rich splicing factor 1

1

15

Small-scale

0.445

High

993807

SRSF4
Serine/arginine-rich splicing factor 4

1

12

Small-scale

0.445

High

1028780

SRSF5
Serine/arginine-rich splicing factor 5

1

14

Small-scale

0.445

High

1029048

SRSF6
Serine/arginine-rich splicing factor 6

1

16

Small-scale

0.445

High

1084377

SRSF7
Serine/arginine-rich splicing factor 7

1

15

Small-scale

0.445

High

670482

GNA11
Guanine nucleotide-binding protein subunit alpha-11

1

2

High-throughput

0.437

High

980312

K1C17
Keratin, type I cytoskeletal 17

1

8

High-throughput

0.437

High

1301918

GBB4
Guanine nucleotide-binding protein subunit beta-4

1

2

High-throughput

0.437

High

570273

NEUM
Neuromodulin

3

0

High-throughput

0.347

High

617139

PTPRG
Receptor-type tyrosine-protein phosphatase gamma

3

0

High-throughput

0.347

High

1018306

CNTN1
Contactin-1

3

0

High-throughput

0.347

High

1250949

OCC1
Overexpressed in colon carcinoma 1 protein

2

0

High-throughput

0.328

High

1262325

PIHD2
PIH1 domain-containing protein 2

2

0

High-throughput

0.316

High

991113

PIGF
Phosphatidylinositol-glycan biosynthesis class F protein

1

0

High-throughput

0.279

Low

1301917

CB39L
Calcium-binding protein 39-like

1

0

High-throughput

0.279

Low

1301919

OCAD1
OCIA domain-containing protein 1

1

0

High-throughput

0.279

Low

506206

PYGB
Glycogen phosphorylase, brain form

1

0

High-throughput

0.249

Low

1077694

NSDHL
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating

1

0

High-throughput

0.249

Low

1266075

ASM3B
Acid sphingomyelinase-like phosphodiesterase 3b

1

0

High-throughput

0.249

Low

1301920

ABCF2
ATP-binding cassette sub-family F member 2

1

0

High-throughput

0.249

Low

1301924

EPCR
Endothelial protein C receptor

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024