HitPredict

Interactor 1: STK25 (O00506)
Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Ste20-like kinase) (Sterile 20/oxidant stress-response kinase 1) (SOK-1) (Ste20/oxidant stress response kinase 1)
Gene: STK25

Interactor 2: 1433Z (P63104)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: YWHAZ

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	15037601
Identification Methods	protein kinase assay
Interaction Type	phosphorylation reaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0006468 - protein phosphorylation GO:0007165 - signal transduction GO:0051683 - establishment of Golgi localization GO:0070062 - extracellular exosome and 1 others more... GO:0090168 - Golgi reassembly
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 426 Hs			1 245
+	Hs
		131551 STK25_HUMAN (1-426): 4.51e-156: 449: 100.00		1433B_HUMAN (1-242): 9.01e-140: 393: 87.60
+	At
		965360 CIPKC_ARATH (8-419): 2.89e-137: 403: 20.14		14332_ARATH (3-239): 6.89e-143: 401: 65.15
+	At
		1280891 CIPKC_ARATH (8-419): 2.89e-137: 403: 20.14		14337_ARATH (2-238): 9.2e-142: 399: 62.66
+	At
		788672 CIPKC_ARATH (8-419): 2.89e-137: 403: 20.14		14333_ARATH (3-239): 1.48e-141: 398: 64.73
+	Hs
		681776 AKT1_HUMAN (6-330): 4.86e-131: 387: 25.75		1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00
+	Hs
		681770 AKT1_HUMAN (6-330): 4.86e-131: 387: 25.75		1433E_HUMAN (2-241): 9.9e-144: 403: 68.18
+	Hs
		568620 KAPCA_HUMAN (4-322): 7.9e-132: 384: 22.32		1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00
+	Hs
		568616 KAPCA_HUMAN (4-322): 7.9e-132: 384: 22.32		1433E_HUMAN (2-241): 9.9e-144: 403: 68.18
+	Hs
		909512 STK3_HUMAN (2-295): 3.42e-128: 380: 51.01		1433E_HUMAN (2-241): 9.9e-144: 403: 68.18
+	Hs
		909502 STK4_HUMAN (3-284): 1.11e-127: 379: 52.80		1433E_HUMAN (2-241): 9.9e-144: 403: 68.18
+	Hs
		610682 KAPCB_HUMAN (4-315): 1.97e-131: 383: 23.75		1433T_HUMAN (1-245): 2.6e-140: 395: 79.59
+	Hs
		646859 STK3_HUMAN (2-295): 3.42e-128: 380: 51.01		1433T_HUMAN (1-245): 2.6e-140: 395: 79.59
+	Hs
		646852 STK4_HUMAN (3-284): 1.11e-127: 379: 52.80		1433T_HUMAN (1-245): 2.6e-140: 395: 79.59
+	Hs
		683316 STK3_HUMAN (2-295): 3.42e-128: 380: 51.01		1433B_HUMAN (1-242): 9.01e-140: 393: 87.60
+	Hs
		683308 STK4_HUMAN (3-284): 1.11e-127: 379: 52.80		1433B_HUMAN (1-242): 9.01e-140: 393: 87.60
+	Hs
		681766 AKT1_HUMAN (6-330): 4.86e-131: 387: 25.75		1433G_HUMAN (1-240): 2.37e-108: 314: 74.59
+	Hs
		904517 STK3_HUMAN (2-295): 3.42e-128: 380: 51.01		1433G_HUMAN (1-240): 2.37e-108: 314: 74.59
+	Hs
		904507 STK4_HUMAN (3-284): 1.11e-127: 379: 52.80		1433G_HUMAN (1-240): 2.37e-108: 314: 74.59
+	Hs
		981974 STK3_HUMAN (2-295): 3.42e-128: 380: 51.01		1433F_HUMAN (2-240): 1.26e-107: 312: 74.49
+	Hs
		681682 AKT1_HUMAN (6-330): 4.86e-131: 387: 25.75		1433S_HUMAN (1-237): 8.27e-104: 302: 71.97