Interactor 1: NEDD4 (Q9VVI3)
E3 ubiquitin-protein ligase Nedd-4 (DNedd4) (EC 2.3.2.26) (HECT-type E3 ubiquitin transferase NEDD4)
Gene: NEDD4

Interactor 2: SUDX (Q9Y0H4)
E3 ubiquitin-protein ligase Su(dx) (EC 2.3.2.26) (HECT-type E3 ubiquitin transferase Su(dx)) (Protein suppressor of deltex)
Gene: Su(dx)

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.54 1.00 0.737

The method score is based on:

Property Details
Experiments 22036573, 38944040
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains C2~C2, HECT~HECT, HECT~WW, WW~WW
Common GO terms GO:0004842 - ubiquitin-protein transferase activity
GO:0005112 - Notch binding
GO:0005737 - cytoplasm
GO:0007219 - Notch signaling pathway
GO:0008586 - imaginal disc-derived wing vein morphogenesis
and 6 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 1007
Dm

1 949
+ Dm
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+ Mm
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Last updated: 11Aug2025