HitPredict

Interactor 1: PLK1 (P53350)
Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13)
Gene: PLK1

Interactor 2: RHG05 (Q13017)
Rho GTPase-activating protein 5 (Rho-type GTPase-activating protein 5) (p190-B)
Gene: ARHGAP5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	28514442, 25659891, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 603 Hs			1 1502
+	Hs
		861922 PLK1_HUMAN (1-603): 0: 617: 100.00		RGAP1_HUMAN (1056-1491): 1.06e-69: 249: 18.85
+	Ce
		711268 PLK1_CAEEL (22-599): 0: 536: 50.58		PAC1_CAEEL (1136-1475): 3.46e-61: 233: 21.94
+	Hs
		506554 PLK1_HUMAN (1-603): 0: 617: 100.00		BCR_HUMAN (1250-1420): 2.54e-20: 100: 31.79
+	Hs
		682206 AKT2_HUMAN (18-356): 6.81e-134: 401: 26.51		RGAP1_HUMAN (1056-1491): 1.06e-69: 249: 18.85
+	Hs
		154703 AURKA_HUMAN (28-307): 4.39e-43: 160: 32.17		TCRG1_HUMAN (226-547): 1.18e-18: 94.9: 12.50