Interactor 1: DCP1B (Q8IZD4)
mRNA-decapping enzyme 1B (EC 3.6.1.62)
Gene: DCP1B

Interactor 2: DCP1A (Q9NPI6)
mRNA-decapping enzyme 1A (EC 3.6.1.62) (Smad4-interacting transcriptional co-activator) (Transcription factor SMIF)
Gene: DCP1A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.92 1.00 0.963

The method score is based on:

Property Details
Experiments 24981860, 35271311, 16364915, 24778252, 25036637, 29395067, 19966221
Identification Methods affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains DCP1~DCP1, mRNA_decap_C~mRNA_decap_C
Common GO terms GO:0000184 - nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0000290 - deadenylation-dependent decapping of nuclear-transcribed mRNA
GO:0000932 - P-body
GO:0003729 - mRNA binding
GO:0005634 - nucleus
and 5 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 617
Hs

1 582
+ Hs
+ Hs
+ Dm
+ At
+ Sp
+ Mm
+ Hs
+ Hs
+ Mm
+ Dm

Service provided by Combinatics, Japan

Last updated: 11Aug2025