Protein: DCP1B
mRNA-decapping enzyme 1B (EC 3.6.1.62)

Gene: DCP1B
Organism: Homo sapiens
Interactions: 112
UniProt ID: Q8IZD4

Gene Ontology (top 5):
GO:0000184 - nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0000290 - deadenylation-dependent decapping of nuclear-transcribed mRNA
GO:0000932 - P-body
GO:0003729 - mRNA binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1306898

DCP2
m7GpppN-mRNA hydrolase

7

3

Small-scale

0.965

High

1316194

DCP1A
mRNA-decapping enzyme 1A

7

10

Small-scale

0.963

High

1316195

PNRC2
Proline-rich nuclear receptor coactivator 2

2

3

High-throughput

0.776

High

1316181

EDC3
Enhancer of mRNA-decapping protein 3

13

3

Small-scale

0.763

High

684304

DDX6
Probable ATP-dependent RNA helicase DDX6

8

9

Small-scale

0.754

High

1049541

1433F
14-3-3 protein eta

4

20

High-throughput

0.699

High

966595

1433G
14-3-3 protein gamma

4

20

High-throughput

0.697

High

336717

BAG4
BAG family molecular chaperone regulator 4

4

1

High-throughput

0.694

High

1241467

EDC4
Enhancer of mRNA-decapping protein 4

4

10

Small-scale

0.692

High

541040

PIM1
Serine/threonine-protein kinase pim-1

4

2

High-throughput

0.691

High

705457

GRN
Progranulin

3

1

High-throughput

0.667

High

1094584

UBP4
Ubiquitin carboxyl-terminal hydrolase 4

3

2

High-throughput

0.662

High

891670

GSK3B
Glycogen synthase kinase-3 beta

3

6

High-throughput

0.650

High

253968

LPXN
Leupaxin

2

7

High-throughput

0.628

High

891239

GSK3A
Glycogen synthase kinase-3 alpha

2

5

High-throughput

0.620

High

1085965

PNRC1
Proline-rich nuclear receptor coactivator 1

1

3

High-throughput

0.618

High

483147

CLCA
Clathrin light chain A

2

5

High-throughput

0.611

High

1316201

TNR6B
Trinucleotide repeat-containing gene 6B protein

2

10

High-throughput

0.611

High

1316184

F167A
Protein FAM167A

3

1

High-throughput

0.604

High

1316186

ERP44
Endoplasmic reticulum resident protein 44

3

4

High-throughput

0.604

High

1252852

ZN704
Zinc finger protein 704

2

0

High-throughput

0.602

High

1306940

I2BP1
Interferon regulatory factor 2-binding protein 1

2

0

High-throughput

0.602

High

730042

1433B
14-3-3 protein beta/alpha

2

20

High-throughput

0.601

High

688278

TTP
mRNA decay activator protein ZFP36

2

5

Small-scale

0.586

High

1316170

XRN1
5'-3' exoribonuclease 1

2

3

High-throughput

0.586

High

1316173

LS14A
Protein LSM14 homolog A

2

10

High-throughput

0.584

High

1316169

DCP1B
mRNA-decapping enzyme 1B

1

15

Small-scale

0.575

High

1316183

BOD1
Biorientation of chromosomes in cell division protein 1

2

3

High-throughput

0.558

High

1316178

FAN
Protein FAN

1

6

Small-scale

0.552

High

928890

LIPR2
Pancreatic lipase-related protein 2

2

2

High-throughput

0.549

High

175112

SC16A
Protein transport protein Sec16A

1

8

High-throughput

0.536

High

384479

CRYAA
Alpha-crystallin A chain

1

3

High-throughput

0.536

High

483365

CLCB
Clathrin light chain B

1

5

High-throughput

0.536

High

650852

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

1

8

High-throughput

0.536

High

761447

HS71L
Heat shock 70 kDa protein 1-like

1

3

Small-scale

0.536

High

791520

SYUA
Alpha-synuclein

1

2

Small-scale

0.536

High

848520

MAGA8
Melanoma-associated antigen 8

1

2

High-throughput

0.536

High

971764

1433E
14-3-3 protein epsilon

1

3

High-throughput

0.536

High

990479

1433Z
14-3-3 protein zeta/delta

1

20

High-throughput

0.536

High

997847

CSK21
Casein kinase II subunit alpha

1

10

High-throughput

0.536

High

1100887

G3BP1
Ras GTPase-activating protein-binding protein 1

1

1

High-throughput

0.536

High

1316188

MLP3A
Microtubule-associated protein 1 light chain 3 alpha

1

3

High-throughput

0.536

High

1316200

G3BP2
Ras GTPase-activating protein-binding protein 2

1

1

High-throughput

0.536

High

776985

PPM1A
Protein phosphatase 1A

1

0

High-throughput

0.513

High

948071

GBG2
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2

1

0

High-throughput

0.513

High

1316209

CEPT1
Choline/ethanolaminephosphotransferase 1

1

0

High-throughput

0.513

High

1106604

SMAD4
Mothers against decapentaplegic homolog 4

1

5

High-throughput

0.508

High

1316191

RENT2
Regulator of nonsense transcripts 2

1

1

High-throughput

0.508

High

1228677

C102B
Coiled-coil domain-containing protein 102B

1

6

High-throughput

0.489

High

1315510

BD1L2
Biorientation of chromosomes in cell division protein 1-like 2

1

3

High-throughput

0.489

High

1316179

E2F7
Transcription factor E2F7

1

9

High-throughput

0.489

High

344558

LSM8
U6 snRNA-associated Sm-like protein LSm8

1

3

High-throughput

0.481

High

1209098

EXOS6
Exosome complex component MTR3

1

1

High-throughput

0.481

High

64886

RCCD1
RCC1 domain-containing protein 1

1

2

High-throughput

0.479

High

173049

XPO1
Exportin-1

1

7

High-throughput

0.479

High

176511

GRRE1
Granule associated Rac and RHOG effector protein 1

1

1

High-throughput

0.479

High

349153

LATS1
Serine/threonine-protein kinase LATS1

1

3

High-throughput

0.479

High

459671

PROF1
Profilin-1

1

3

High-throughput

0.479

High

550356

PABP1
Polyadenylate-binding protein 1

1

7

High-throughput

0.479

High

589126

RFA2
Replication protein A 32 kDa subunit

1

7

High-throughput

0.479

High

613393

VINC
Vinculin

1

2

High-throughput

0.479

High

878508

PAXI
Paxillin

1

6

High-throughput

0.479

High

888182

MCM2
DNA replication licensing factor MCM2

1

1

High-throughput

0.479

High

942742

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

12

High-throughput

0.479

High

960484

PSME3
Proteasome activator complex subunit 3

1

1

High-throughput

0.479

High

1102018

PABP4
Polyadenylate-binding protein 4

1

7

High-throughput

0.479

High

1149325

STIL
SCL-interrupting locus protein

1

1

High-throughput

0.479

High

1156144

ZYX
Zyxin

1

7

High-throughput

0.479

High

1165467

CPEB4
Cytoplasmic polyadenylation element-binding protein 4

1

11

High-throughput

0.479

High

1252120

SYNE3
Nesprin-3

1

5

High-throughput

0.479

High

1252329

MEX3B
RNA-binding protein MEX3B

1

2

High-throughput

0.479

High

1275556

ZCCHV
Zinc finger CCCH-type antiviral protein 1

1

14

High-throughput

0.479

High

1280689

YTHD3
YTH domain-containing family protein 3

1

9

High-throughput

0.479

High

1287094

PATL1
Protein PAT1 homolog 1

1

12

High-throughput

0.479

High

1316171

RHG18
Rho GTPase-activating protein 18

1

5

High-throughput

0.479

High

1316174

TNR6A
Trinucleotide repeat-containing gene 6A protein

1

20

High-throughput

0.479

High

1316175

NUP35
Nucleoporin NUP35

1

2

High-throughput

0.479

High

1316176

TNIP2
TNFAIP3-interacting protein 2

1

1

High-throughput

0.479

High

1316177

ATX2L
Ataxin-2-like protein

1

12

High-throughput

0.479

High

1316185

ATX2
Ataxin-2

1

10

High-throughput

0.479

High

1316187

CPEB1
Cytoplasmic polyadenylation element-binding protein 1

1

8

High-throughput

0.479

High

1316192

CPAP
Centrosomal P4.1-associated protein

1

3

High-throughput

0.479

High

1316193

MOV10
Helicase MOV-10

1

2

High-throughput

0.479

High

1316198

ZRAN1
Ubiquitin thioesterase ZRANB1

1

5

High-throughput

0.479

High

1316202

FBW1A
F-box/WD repeat-containing protein 1A

1

6

High-throughput

0.479

High

1316203

NINL
Ninein-like protein

1

7

High-throughput

0.479

High

1316204

CBY1
Protein chibby homolog 1

1

1

High-throughput

0.479

High

1316205

MARF1
Meiosis regulator and mRNA stability factor 1

1

1

High-throughput

0.479

High

1316207

YTHD2
YTH domain-containing family protein 2

1

10

High-throughput

0.479

High

1277852

NUFP2
FMR1-interacting protein NUFIP2

1

0

High-throughput

0.458

High

3678

NBDY
Negative regulator of P-body association

1

1

Small-scale

0.445

High

537491

HSP7C
Heat shock cognate 71 kDa protein

1

3

High-throughput

0.445

High

691231

1433T
14-3-3 protein theta

1

20

High-throughput

0.445

High

1234857

PKHA7
Pleckstrin homology domain-containing family A member 7

1

16

High-throughput

0.445

High

1258501

CR3L2
Cyclic AMP-responsive element-binding protein 3-like protein 2

1

2

High-throughput

0.445

High

1316182

DYL2
Dynein light chain 2, cytoplasmic

1

3

High-throughput

0.445

High

768619

RFA3
Replication protein A 14 kDa subunit

1

5

High-throughput

0.437

High

1187045

LSM12
Protein LSM12

1

2

High-throughput

0.437

High

1225000

KANK2
KN motif and ankyrin repeat domain-containing protein 2

1

5

High-throughput

0.437

High

1316180

Q96BE0
Heat shock cognate 71 kDa protein

1

4

High-throughput

0.437

High

1316189

PKHA4
Pleckstrin homology domain-containing family A member 4

1

13

High-throughput

0.437

High

1316196

KI13B
Kinesin-like protein KIF13B

1

6

High-throughput

0.437

High

1316197

CING
Cingulin

1

4

High-throughput

0.437

High

1316206

KCTD3
BTB/POZ domain-containing protein KCTD3

1

10

High-throughput

0.437

High

1239238

ARMC6
Armadillo repeat-containing protein 6

1

0

High-throughput

0.426

High

1316199

PNMA2
Paraneoplastic antigen Ma2

1

1

High-throughput

0.407

High

1309775

CCD60
Coiled-coil domain-containing protein 60

2

0

High-throughput

0.328

High

938878

SH3BG
SH3 domain-binding glutamic acid-rich protein

2

0

High-throughput

0.319

High

1316172

MIA40
Mitochondrial intermembrane space import and assembly protein 40

1

0

High-throughput

0.279

Low

1316190

CH033
UPF0488 protein C8orf33

1

0

High-throughput

0.279

Low

1316208

HS3S4
Heparan sulfate glucosamine 3-O-sulfotransferase 4

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025