HitPredict

Interactor 1: AFG32 (Q8JZQ2)
Mitochondrial inner membrane m-AAA protease component AFG3L2 (EC 3.4.24.-) (EC 3.6.-.-) (AFG3-like protein 2)
Gene: Afg3l2

Interactor 2: AFG32 (Q8JZQ2)
Mitochondrial inner membrane m-AAA protease component AFG3L2 (EC 3.4.24.-) (EC 3.6.-.-) (AFG3-like protein 2)
Gene: Afg3l2

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.68 1.00 0.827

The method score is based on:

Property Details
Experiments 29199018, 29222160, 28130547
Identification Methods cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains AAA~AAA, AAA~AAA_lid_3, AAA~Peptidase_M41, AAA_lid_3~AAA_lid_3, AAA_lid_3~Peptidase_M41, FtsH_ext~FtsH_ext, Peptidase_M41~Peptidase_M41
Common GO terms GO:0004176 - ATP-dependent peptidase activity
GO:0004222 - metalloendopeptidase activity
GO:0005524 - ATP binding
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
and 26 others

more...
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 802
Mm

1 802
+ Mm
+ At
+ Sc
+ At
+ Mm
+ Sc
+ Ec
+ Mm
+ At
+ Pf
+ At
+ At
+ Rn
+ At
+ Tm

Service provided by Combinatics, Japan

Last updated: 11Aug2025