Interactor 1: YME1 (P32795)
Mitochondrial inner membrane i-AAA protease supercomplex subunit YME1 (EC 3.4.24.-) (Protein OSD1) (Tat-binding homolog 11) (Yeast mitochondrial escape protein 1)
Gene: YME1
Interactor 2: AFG3 (P39925)
Mitochondrial inner membrane m-AAA protease component YTA10 (EC 3.4.24.-) (EC 3.6.-.-) (ATPase family gene 3 protein) (Tat-binding homolog 10)
Gene: AFG3
Species: Saccharomyces cerevisiae S288C
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 18843051 |
| Identification Methods | affinity chromatography technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | AAA~AAA, AAA~AAA_lid_3, AAA~Peptidase_M41, AAA_lid_3~AAA_lid_3, AAA_lid_3~Peptidase_M41, Peptidase_M41~Peptidase_M41 |
| Common GO terms | GO:0004176 - ATP-dependent peptidase activity GO:0004222 - metalloendopeptidase activity GO:0005524 - ATP binding GO:0005739 - mitochondrion GO:0005743 - mitochondrial inner membrane and 4 others more... |
| Homologous interactions | 15 |
Homologous interactions
Color coding for hit scores 
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| + | Sc |   |
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| + | Mm | |
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| + | Mm | |
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| + | At | |
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| + | Mm | |
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| + | At | |
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| + | Ec | |
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| + | Mm | |
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| + | Pf | |
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| + | Tm | |
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| + | At | |
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| + | At | |
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| + | At | |
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| + | Sc | |
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
